Burden of chronic cough on social participation, healthcare resource utilisation and activities of daily living in the Canadian Longitudinal Study on Aging (CLSA).

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
Read More Add to Saved list
  • Additional Information
    • Source:
      Publisher: Elsevier Country of Publication: England NLM ID: 8908438 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-3064 (Electronic) Linking ISSN: 09546111 NLM ISO Abbreviation: Respir Med Subsets: MEDLINE
    • Publication Information:
      Publication: 2003- : Oxford : Elsevier
      Original Publication: London : Baillière Tindall, in association with the British Thoracic Society, [c1989-
    • Subject Terms:
      Activities of Daily Living* ; Social Participation*; Male ; Female ; Humans ; Longitudinal Studies ; Cough/epidemiology ; Cough/therapy ; Canada/epidemiology ; Aging ; Patient Acceptance of Health Care
    • Abstract:
      Background: Chronic cough is a common troublesome condition, but it is unclear whether dry or productive chronic cough and sex, impacts the burden of cough differently.
      Methods: The Canadian Longitudinal Study on Aging is a nationally generalizable, stratified random sample of adults aged 45-85 years. Chronic cough was identified based on a self-reported daily cough in the last 12 months assessed at baseline (2011-2015) and follow-up (2015-2018). Odds ratios (95 % CI) for cough status and change in social participation activities (SPA), healthcare resource utilisation (HCRU), basic activities of daily living (ADLs) and instrumental activities of daily living (IADLs) were estimated using a weighted generalised estimating equation (WGEE). Results were stratified by sex, and adjusted for age, sex, smoking, body mass index, education, respiratory diseases and retirement status.
      Results: Overall, chronic cough was associated with less SPA, greater HCRU and impaired ADL/IADLs. Productive chronic cough in males was associated with SPA limited by health, ED visits and hospitalisation. Females with productive chronic cough was associated with reduced frequency of SPA and ED visit. Dry chronic cough in females was associated with SPA limited by health and ED visits. Both types of cough was associated with at least 1 impaired basic ADL, but only in females with productive chronic cough was there an association with any impairment in IADLs.
      Conclusion: Chronic cough is associated with a greater burden on social participation, healthcare use and personal care.
      Competing Interests: Declaration of competing interest All authors have completed the ICMJE uniform disclosure form. I.S. reports grants and personal fees from Merck Canada and GSK, grants from Bayer and Bellus, personal fees from Respiplus, Genentech, and AstraZeneca, outside the submitted work; P.O.B. reports grants and personal fees from AstraZeneca, personal fees from GSK, grants from Novartis, grants and personal fees from Medimmune, personal fees from Chiesi, outside the submitted work. The other authors have no conflicts of interest to declare.
      (Copyright © 2023 Elsevier Ltd. All rights reserved.)
    • Comments:
      Erratum in: Respir Med. 2024 Mar;223:107556. (PMID: 38354487)
    • Contributed Indexing:
      Keywords: CLSA; Chronic cough; Epidemiology; Quality of life
    • Publication Date:
      Date Created: 20231025 Date Completed: 20231124 Latest Revision: 20240423
    • Publication Date:
      20240423
    • Accession Number:
      10.1016/j.rmed.2023.107431
    • Accession Number:
      37879447