Prevalence of Neisseria gonorrhoeae and Chlamydia trachomatis infections among adolescent men who have sex with men and transgender women in Salvador, Northeast Brazil.

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
Read More Add to Saved list
  • Additional Information
    • Source:
      Publisher: Cambridge University Press Country of Publication: England NLM ID: 8703737 Publication Model: Electronic Cited Medium: Internet ISSN: 1469-4409 (Electronic) Linking ISSN: 09502688 NLM ISO Abbreviation: Epidemiol Infect Subsets: MEDLINE
    • Publication Information:
      Original Publication: Cambridge Eng : Cambridge University Press
    • Subject Terms:
      Transgender Persons* ; Sexual and Gender Minorities* ; Chlamydia Infections*/epidemiology ; Gonorrhea*/epidemiology; Male ; Humans ; Adolescent ; Female ; Neisseria gonorrhoeae ; Chlamydia trachomatis ; Homosexuality, Male ; Prevalence ; Brazil/epidemiology
    • Abstract:
      Adolescent men who have sex with men (AMSM) and transgender women (ATGW) enrolled as part of the PrEP1519 study between April 2019 and February 2021 in Salvador were tested for Neisseria gonorrhoeae (NG) and Chlamydia trachomatis (CT) infections.We performed real-time polymerase chain reaction using oropharyngeal, anal, and urethral swabs; assessed factors associated with NG and CT infections using multivariable Poisson regression analysis with robust variance; and estimated the prevalence ratios (PRs) and 95% confidence intervals (95% CIs). In total, 246 participants were included in the analyses (median age: 18.8; IQR: 18.2-19.4 years). The overall oropharyngeal, anal, and urethral prevalence rates of NG were 17.9%, 9.4%, 7.6%, and 1.9%, respectively. For CT, the overall, oropharyngeal, anal, and urethral prevalence rates were 5.9%, 1.2%, 2.4%, and 1.9%, respectively. A low level of education, clinical suspicion of STI (and coinfection with Mycoplasma hominis were associated with NG infection. The prevalence of NG and CT, especially extragenital infections, was high in AMSM and ATGW. These findings highlight the need for testing samples from multiple anatomical sites among adolescents at a higher risk of STI acquisition, implementation of school-based strategies, provision of sexual health education, and reduction in barriers to care.
    • References:
      BMC Infect Dis. 2023 Apr 18;23(1):244. (PMID: 37072756)
      J Adolesc Health. 2019 Jan;64(1):36-42. (PMID: 30292649)
      MMWR Morb Mortal Wkly Rep. 2018 Sep 14;67(36):1007-1011. (PMID: 30212446)
      BMJ Open. 2020 Mar 16;10(3):e033976. (PMID: 32184310)
      Lancet HIV. 2017 Apr;4(4):e169-e176. (PMID: 28188030)
      BMJ Open. 2021 Sep 2;11(9):e047856. (PMID: 34475162)
      Int Urol Nephrol. 2019 Jun;51(6):901-907. (PMID: 30953260)
      Sex Transm Dis. 2019 Nov;46(11):737-742. (PMID: 31453926)
      Cad Saude Publica. 2023 Mar 27;39Suppl 1(Suppl 1):e00143221. (PMID: 36995865)
      Bull World Health Organ. 2019 Aug 01;97(8):548-562P. (PMID: 31384073)
      Methods Mol Biol. 1998;104:141-4. (PMID: 9711650)
      Am Fam Physician. 2015 Jun 15;91(12):844-51. (PMID: 26131944)
      Infect Dis Obstet Gynecol. 2016;2016:5758387. (PMID: 27366021)
      J Acquir Immune Defic Syndr. 2020 Jul 1;84(3):280-284. (PMID: 32149857)
      Sex Transm Dis. 2020 Jul;47(7):484-490. (PMID: 32355108)
      BMC Public Health. 2015 Jul 21;15:686. (PMID: 26195002)
      Sex Health. 2013 Jul;10(3):199-203. (PMID: 23751932)
      BMC Infect Dis. 2020 Feb 7;20(1):110. (PMID: 32033533)
      Arch Sex Behav. 2023 Feb;52(2):703-719. (PMID: 35876978)
      MMWR Recomm Rep. 2015 Jun 5;64(RR-03):1-137. (PMID: 26042815)
      Biomedica. 2015 Jul-Sep;35(3):314-24. (PMID: 26849693)
      PLoS Med. 2018 Feb 27;15(2):e1002512. (PMID: 29485985)
      Rev Soc Bras Med Trop. 2010 Sep-Oct;43(5):500-3. (PMID: 21085857)
      J Int AIDS Soc. 2021 Feb;24(2):e25673. (PMID: 33605081)
      Indian J Med Microbiol. 2021 Jan;39(1):88-97. (PMID: 33610259)
      MMWR Recomm Rep. 2014 Mar 14;63(RR-02):1-19. (PMID: 24622331)
      Rev Bras Enferm. 2020 Sep 21;73(suppl 4):e20190242. (PMID: 32965409)
      Curr Opin Pediatr. 2018 Feb;30(1):137-143. (PMID: 29315111)
      MMWR Surveill Summ. 2018 Jun 15;67(8):1-114. (PMID: 29902162)
      PLoS One. 2015 Dec 08;10(12):e0143304. (PMID: 26646541)
      J Sch Health. 2015 Mar;85(3):189-96. (PMID: 25611941)
      Int J STD AIDS. 2012 Sep;23(9):626-31. (PMID: 23033514)
    • Contributed Indexing:
      Keywords: Adolescents; STIs; chlamydia; gonorrhea; men who have sex with men; prevalence; transgender women
    • Publication Date:
      Date Created: 20231023 Date Completed: 20231206 Latest Revision: 20231221
    • Publication Date:
      20231221
    • Accession Number:
      PMC10728983
    • Accession Number:
      10.1017/S095026882300170X
    • Accession Number:
      37869965