Is cardioplegia system pressure the optimal measure of coronary perfusion during antegrade cardioplegia delivery? A critical review of pressure measurements for optimal antegrade delivery.

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  • Additional Information
    • Source:
      Publisher: SAGE Publications Country of Publication: England NLM ID: 8700166 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-111X (Electronic) Linking ISSN: 02676591 NLM ISO Abbreviation: Perfusion Subsets: MEDLINE
    • Publication Information:
      Publication: London : SAGE Publications
      Original Publication: [London] : Edward Arnold, [c1986-
    • Subject Terms:
      Heart Arrest, Induced*/methods; Humans ; Male ; Female ; Coronary Artery Bypass/methods ; Cardioplegic Solutions/administration & dosage ; Coronary Circulation ; Cardiopulmonary Bypass/methods ; Cardiopulmonary Bypass/instrumentation
    • Abstract:
      Antegrade cardioplegia is routinely given during cardiac surgery. The delivery of antegrade cardioplegia from the cardiopulmonary bypass machine has many variables. Many perfusionists rely exclusively on cardioplegia system pressure to ensure safe antegrade delivery. Our group reviewed antegrade cardioplegia delivery in 50 patients undergoing coronary artery bypass graft. The data collected included the cardioplegia system pressure and the patient's direct aortic root pressure. The analysis of the data found weak correlation between the two pressures with a large mean difference and a wide standard deviation. The results suggest the direct measurement of aortic root pressure as guidance to antegrade cardioplegia instead of relying solely on cardioplegia system pressure.
      Competing Interests: Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
    • Contributed Indexing:
      Keywords: Antegrade cardioplegia; aortic root pressure; cardioplegia system pressure; internal resistance; “zero-resistance”
    • Accession Number:
      0 (Cardioplegic Solutions)
    • Publication Date:
      Date Created: 20231019 Date Completed: 20241018 Latest Revision: 20241123
    • Publication Date:
      20241123
    • Accession Number:
      10.1177/02676591231206016
    • Accession Number:
      37855099