Total intravenous anesthesia decreases hospital stay but not incidence of postoperative pulmonary complications after lung resection surgery: a propensity score matching study.

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  • Additional Information
    • Source:
      Publisher: BioMed Central Country of Publication: England NLM ID: 100968535 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2253 (Electronic) Linking ISSN: 14712253 NLM ISO Abbreviation: BMC Anesthesiol Subsets: MEDLINE
    • Publication Information:
      Original Publication: [London] : BioMed Central, 2001-
    • Subject Terms:
      Postoperative Nausea and Vomiting*/chemically induced ; Propofol*/adverse effects; Humans ; Anesthetics, Intravenous/adverse effects ; Incidence ; Anesthesia, Intravenous ; Length of Stay ; Retrospective Studies ; Propensity Score ; Anesthesia, General/adverse effects ; Lung
    • Abstract:
      Background: There is no consensus regarding the superiority of volatile or total intravenous anesthesia (TIVA) in reducing the incidence of postoperative pulmonary complications (PPCs) after lung resection surgery (LRS). Thus, the aim of this study was to investigate the different anesthetic regimens and the incidence of PPCs in patients who underwent LRS. We hypothesized that TIVA is associated with a lower incidence of PPCs than volatile anesthesia.
      Methods: This was a retrospective cohort study of patients who underwent LRS at Taipei Veterans General Hospital between January 2016 and December 2020. The patients' charts were reviewed and data on patient characteristics, perioperative features, and postoperative outcomes were extracted and analyzed. The patients were categorized into TIVA or volatile anesthesia groups and their clinical data were compared. Propensity score matching was performed to reduce potential selection bias. The primary outcome was the incidence of PPCs, whereas the secondary outcomes were the incidences of other postoperative events, such as length of hospital stay (LOS) and postoperative nausea and vomiting (PONV).
      Results: A total of 392 patients each were included in the TIVA and volatile anesthesia groups. There was no statistically significant difference in the incidence of PPCs between the volatile anesthesia and TIVA groups. The TIVA group had a shorter LOS (p < 0.001) and a lower incidence of PONV than the volatile anesthesia group (4.6% in the TIVA group vs. 8.2% in the volatile anesthesia group; p = 0.041). However, there were no significant differences in reintubation, 30-day readmission, and re-operation rates between the two groups.
      Conclusions: There was no significant difference between the incidence of PPCs in patients who underwent LRS under TIVA and that in patients who underwent LRS under volatile anesthesia. However, TIVA had shorter LOS and lower incidence of PONV which may be a better choice for maintenance of anesthesia in patients undergoing LRS.
      (© 2023. BioMed Central Ltd., part of Springer Nature.)
    • References:
      Br J Anaesth. 2012 Nov;109(5):742-53. (PMID: 23035051)
      Anesth Analg. 2021 Dec 1;133(6):1391-1401. (PMID: 34784326)
      CA Cancer J Clin. 2021 May;71(3):209-249. (PMID: 33538338)
      Cochrane Database Syst Rev. 2018 Aug 21;8:CD012317. (PMID: 30129968)
      PLoS One. 2018 Apr 13;13(4):e0195901. (PMID: 29652932)
      Braz J Anesthesiol. 2021 Jul-Aug;71(4):333-338. (PMID: 34229858)
      J Thorac Dis. 2022 Jul;14(7):2712-2720. (PMID: 35928616)
      J Thorac Dis. 2020 Nov;12(11):6670-6679. (PMID: 33282368)
      Anesthesiology. 2016 Jun;124(6):1230-45. (PMID: 27065094)
      Br J Anaesth. 2003 Nov;91(5):631-7. (PMID: 14570783)
      J Hum Reprod Sci. 2012 Jan;5(1):7-13. (PMID: 22870008)
      Stat Med. 1998 Oct 15;17(19):2265-81. (PMID: 9802183)
      Br J Anaesth. 2017 Oct 01;119(4):655-663. (PMID: 29121283)
      Anesth Analg. 2020 Mar;130(3):586-595. (PMID: 31569161)
      J Chest Surg. 2022 Feb 05;55(1):30-36. (PMID: 35115419)
      Br J Anaesth. 2017 Mar 1;118(3):317-334. (PMID: 28186222)
      Anesthesiology. 2016 Aug;125(2):313-21. (PMID: 27203279)
      J Chronic Dis. 1987;40(5):373-83. (PMID: 3558716)
      N Engl J Med. 2004 Jun 10;350(24):2511-2. (PMID: 15190144)
      Eur J Cardiothorac Surg. 2019 Jan 1;55(1):91-115. (PMID: 30304509)
      Anesthesiology. 2015 Apr;122(4):932-46. (PMID: 25587641)
      J Clin Anesth. 2017 Nov;42:19-25. (PMID: 28797751)
    • Contributed Indexing:
      Keywords: Anesthesia; Lung resection surgery; Postoperative pulmonary complications; Total intravenous anesthesia; Volatile anesthesia
    • Accession Number:
      YI7VU623SF (Propofol)
      0 (Anesthetics, Intravenous)
    • Publication Date:
      Date Created: 20231017 Date Completed: 20231023 Latest Revision: 20231121
    • Publication Date:
      20231121
    • Accession Number:
      PMC10580638
    • Accession Number:
      10.1186/s12871-023-02260-4
    • Accession Number:
      37848832