What are the key risk factors of keloid formation after repair of syndactyly of the toe?

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
Read More Add to Saved list
  • Additional Information
    • Source:
      Publisher: Elsevier Country of Publication: Japan NLM ID: 9604934 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1436-2023 (Electronic) Linking ISSN: 09492658 NLM ISO Abbreviation: J Orthop Sci Subsets: MEDLINE
    • Publication Information:
      Publication: 2016- : Tokyo : Elsevier
      Original Publication: Tokyo : Springer-Verlag Tokyo, c1996-
    • Subject Terms:
      Syndactyly*/surgery ; Keloid*/surgery ; Keloid*/etiology ; Toes*/abnormalities ; Toes*/surgery; Humans ; Retrospective Studies ; Male ; Female ; Risk Factors ; Child, Preschool ; Child ; Postoperative Complications ; Adolescent ; Infant
    • Abstract:
      Purpose: Keloid formation in toes area is rare. However, occurrence of this phenomenon in toes after the surgery of syndactyly repair has been reported. Risk factors of keloid formation in toes after syndactyly reconstructions are currently unknown. This study aimed to investigate the risk factors of keloid formation after the surgery of syndactyly repair of the toes.
      Methods: We retrospectively reviewed our case series including patients who were treated surgically at our institution. We hypothesized some key factors of keloid formation and analyzed each of them statistically.
      Results: A total of 105 patients were treated surgically at our hospital, and 9 patients were involved keloid formations after operations. Among our hypothesized key factors, the results of multivariate logistic regression analysis revealed the number of affected web spaces (OR 0.031; 95%CI 0.001-0.684; p = 0.028) was significantly different. Digital enlargement was not a significant factor (OR 17.731; 95%CI 0.686-458.174; p = 0.091).
      Conclusion: Involving multiple web space was associated with keloid formation after syndactyly release, on the other hand, toe enlargement did not show a significant difference. However, the digital enlargement showed high Odds ratio, we could not deny its high relativity for keloid formation. Further investigations are needed to clarify the key risk factors of keloid formation after the surgery of syndactyly repair of the toes.
      Competing Interests: Declaration of competing interest The authors have no conflict of interest.
      (Copyright © 2023 The Japanese Orthopaedic Association. Published by Elsevier B.V. All rights reserved.)
    • Contributed Indexing:
      Keywords: Digital enlargement; Keloid formation; Syndactyly of the toes
    • Publication Date:
      Date Created: 20231014 Date Completed: 20241116 Latest Revision: 20241116
    • Publication Date:
      20241118
    • Accession Number:
      10.1016/j.jos.2023.10.001
    • Accession Number:
      37838596