Sex and Racial Disparities in Peripheral Artery Disease.

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  • Author(s): Divakaran S;Divakaran S; Krawisz AK; Krawisz AK; Secemsky EA; Secemsky EA; Kant S; Kant S
  • Source:
    Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2023 Nov; Vol. 43 (11), pp. 2099-2114. Date of Electronic Publication: 2023 Sep 14.
  • Publication Type:
    Journal Article; Review; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
  • Language:
    English
  • Additional Information
    • Source:
      Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9505803 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4636 (Electronic) Linking ISSN: 10795642 NLM ISO Abbreviation: Arterioscler Thromb Vasc Biol Subsets: MEDLINE
    • Publication Information:
      Publication: 1998- : Baltimore, Md. : Lippincott Williams & Wilkins
      Original Publication: Dallas, TX : American Heart Association, c1995-
    • Subject Terms:
    • Abstract:
      Several studies have shown that women and racial and ethnic minority patients are at increased risk of developing lower extremity peripheral artery disease and suffering adverse outcomes from it, but a knowledge gap remains regarding the underlying causes of these increased risks. Both groups are more likely to be underdiagnosed, have poorly managed contributory comorbidities, and incur disparities in treatment and management postdiagnosis. Opportunities for improvement in the care of women and racial and ethnic minorities with peripheral artery disease include increased rates of screening, higher rates of clinical suspicion (particularly in the absence of typical symptoms of intermittent claudication), and more aggressive risk factor management before and after the diagnosis of peripheral artery disease.
      Competing Interests: Disclosures E.A. Secemsky has received research grants to Beth Israel Deaconess Medical Center (National Institutes of Health [NIH]/National Heart, Lung, and Blood Institute [NHLBI] K23HL150290, Food and Drug Administration, Harvard Medical School’s Shore Faculty Development Award, AstraZeneca, BD, Boston Scientific, Cook, CSI, Laminate Medical, Medtronic, and Philips); and has received consulting fees from Abbott, Bayer, BD, Boston Scientific, Cook, CSI, Endovascular Engineering, Inari, Janssen, Medtronic, Philips, and VentureMed. The other authors report no conflicts.
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    • Grant Information:
      K23 HL150290 United States HL NHLBI NIH HHS; R03 TR004452 United States TR NCATS NIH HHS
    • Contributed Indexing:
      Keywords: cardiovascular diseases; coronary artery disease; ethnic and racial minorities; lipoprotein; myocardial infarction; peripheral artery disease
    • Publication Date:
      Date Created: 20230914 Date Completed: 20231027 Latest Revision: 20240210
    • Publication Date:
      20240210
    • Accession Number:
      PMC10615869
    • Accession Number:
      10.1161/ATVBAHA.123.319399
    • Accession Number:
      37706319