Menu
×
West Ashley Library
Closed
Phone: (843) 766-6635
Wando Mount Pleasant Library
Closed
Phone: (843) 805-6888
Village Library
Closed
Phone: (843) 884-9741
St. Paul's/Hollywood Library
Closed
Phone: (843) 889-3300
Otranto Road Library
Closed
Phone: (843) 572-4094
Mt. Pleasant Library
Closed
Phone: (843) 849-6161
McClellanville Library
Closed
Phone: (843) 887-3699
Keith Summey North Charleston Library
Closed
Phone: (843) 744-2489
John's Island Library
Closed
Phone: (843) 559-1945
Hurd/St. Andrews Library
Closed
Phone: (843) 766-2546
Folly Beach Library
Closed
Phone: (843) 588-2001
Edisto Island Library
Closed
Phone: (843) 869-2355
Dorchester Road Library
Closed
Phone: (843) 552-6466
John L. Dart Library
Closed
Phone: (843) 722-7550
Baxter-Patrick James Island
Closed
Phone: (843) 795-6679
Main Library
2 p.m. – 5 p.m.
Phone: (843) 805-6930
Bees Ferry West Ashley Library
Closed
Phone: (843) 805-6892
Edgar Allan Poe/Sullivan's Island Library
Closed for renovations
Phone: (843) 883-3914
Mobile Library
Closed
Phone: (843) 805-6909
Today's Hours
West Ashley Library
Closed
Phone: (843) 766-6635
Wando Mount Pleasant Library
Closed
Phone: (843) 805-6888
Village Library
Closed
Phone: (843) 884-9741
St. Paul's/Hollywood Library
Closed
Phone: (843) 889-3300
Otranto Road Library
Closed
Phone: (843) 572-4094
Mt. Pleasant Library
Closed
Phone: (843) 849-6161
McClellanville Library
Closed
Phone: (843) 887-3699
Keith Summey North Charleston Library
Closed
Phone: (843) 744-2489
John's Island Library
Closed
Phone: (843) 559-1945
Hurd/St. Andrews Library
Closed
Phone: (843) 766-2546
Folly Beach Library
Closed
Phone: (843) 588-2001
Edisto Island Library
Closed
Phone: (843) 869-2355
Dorchester Road Library
Closed
Phone: (843) 552-6466
John L. Dart Library
Closed
Phone: (843) 722-7550
Baxter-Patrick James Island
Closed
Phone: (843) 795-6679
Main Library
2 p.m. – 5 p.m.
Phone: (843) 805-6930
Bees Ferry West Ashley Library
Closed
Phone: (843) 805-6892
Edgar Allan Poe/Sullivan's Island Library
Closed for renovations
Phone: (843) 883-3914
Mobile Library
Closed
Phone: (843) 805-6909
Patron Login
menu
Item request has been placed!
×
Item request cannot be made.
×
Processing Request
Close-to-lesion transbronchial biopsy: a novel technique to improve suitability of specimens for genetic testing in patients with peripheral pulmonary lesions.
Item request has been placed!
×
Item request cannot be made.
×
Processing Request
- Author(s): Nishii Y;Nishii Y; Sakaguchi T; Sakaguchi T; Esumi S; Esumi S; Esumi M; Esumi M; Nakamura Y; Nakamura Y; Suzuki Y; Suzuki Y; Ito K; Ito K; Fujiwara K; Fujiwara K; Yasui H; Yasui H; Ito A; Ito A; Tarukawa T; Tarukawa T; Tsuruga T; Tsuruga T; D'Alessandro-Gabazza CN; D'Alessandro-Gabazza CN; Yasuma T; Yasuma T; Fujimoto H; Fujimoto H; Asano F; Asano F; Gabazza EC; Gabazza EC; Kobayashi T; Kobayashi T; Taguchi O; Taguchi O; Hataji O; Hataji O
- Source:
Scientific reports [Sci Rep] 2023 Sep 07; Vol. 13 (1), pp. 14724. Date of Electronic Publication: 2023 Sep 07.- Publication Type:
Journal Article- Language:
English - Source:
- Additional Information
- Source: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
- Publication Information: Original Publication: London : Nature Publishing Group, copyright 2011-
- Subject Terms:
- Abstract: Bronchoscopy with radial-probe endobronchial ultrasound, a guide sheath, and electromagnetic navigation can improve the diagnostic yield of peripheral lung nodules. However, the suitability of specimens for genetic analysis remains unsatisfactory. We hypothesized that a transbronchial biopsy performed after closely approaching the bronchoscope tip to the lesion might provide more suitable specimens for genetic analysis. We enrolled 155 patients with peripheral pulmonary lesions who underwent bronchoscopy with a thin or ultrathin bronchoscope. Bronchoscopy was performed using virtual bronchoscopic navigation and radial-probe endobronchial ultrasound with a guide sheath. The bronchoscope tip was placed closer to the lesion during bronchoscopy to collect larger specimens with higher malignant cell content. The patients who underwent a close-to-lesion biopsy had higher rates of overall diagnostic yield, histopathological diagnostic yield, and specimen quality for genetic testing than those who did not. The significant determinants of the specimen's suitability were the close-to-lesion approach, within-the-lesion image, the use of standard 1.9-mm-forceps, and the number of cancer-cell-positive specimens. The significant predictors of the specimen's suitability for genetic analysis were close-to-lesion biopsy and the number of malignant cell-positive tissue samples. This study demonstrates that the close-to-lesion transbronchial biopsy significantly improves the suitability of bronchoscopic specimens for genetic analysis.
(© 2023. Springer Nature Limited.) - References: Chest. 2020 Aug;158(2):797-807. (PMID: 32145245)
Thorax. 2011 Dec;66(12):1072-7. (PMID: 21749984)
Sci Rep. 2023 Feb 1;13(1):1850. (PMID: 36725903)
Respir Res. 2019 Sep 12;20(1):207. (PMID: 31511032)
J Thorac Dis. 2020 Dec;12(12):7675-7682. (PMID: 33447460)
Front Med (Lausanne). 2022 Oct 10;9:989184. (PMID: 36300190)
JAMA. 2014 May 21;311(19):1998-2006. (PMID: 24846037)
Life (Basel). 2023 Jan 28;13(2):. (PMID: 36836710)
Lung Cancer. 2007 Sep;57(3):322-7. (PMID: 17532538)
Diagnostics (Basel). 2021 Feb 25;11(3):. (PMID: 33668993)
Respiration. 2014;88(5):430-40. (PMID: 25402610)
Chest. 2013 May;143(5 Suppl):e142S-e165S. (PMID: 23649436)
J Thorac Dis. 2020 Jun;12(6):3272-3278. (PMID: 32642250)
Am J Respir Crit Care Med. 2015 Aug 15;192(4):468-76. (PMID: 26039792)
Chest. 2007 Aug;132(2):603-8. (PMID: 17573504)
Eur Respir J. 2022 May 26;59(5):. (PMID: 34625482) - Publication Date: Date Created: 20230907 Date Completed: 20230911 Latest Revision: 20231123
- Publication Date: 20231215
- Accession Number: PMC10485017
- Accession Number: 10.1038/s41598-023-41726-w
- Accession Number: 37679360
- Source:
Contact CCPL
Copyright 2022 Charleston County Public Library Powered By EBSCO Stacks 3.3.0 [350.3] | Staff Login
No Comments.