Psychological insulin resistance and its impact on self-management in type II diabetes mellitus patients treated with insulin therapy.

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    • Source:
      Publisher: Wiley Country of Publication: Australia NLM ID: 9613615 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1440-172X (Electronic) Linking ISSN: 13227114 NLM ISO Abbreviation: Int J Nurs Pract
    • Publication Information:
      Original Publication: Carlton, Vic., Australia : Wiley, c1995-
    • Subject Terms:
    • Abstract:
      Aims: Psychological insulin resistance is a common barrier to initiation and persistence with insulin therapy that affects approximately 42.7% of people living with type II diabetes mellitus, which may negatively impact self-management. This study aimed to assess patients' levels of psychological insulin resistance and to identify factors associated with self-management in patients with type II diabetes mellitus treated with insulin therapy.
      Methods: We adopted a cross-sectional design. Subjects from the metabolism and endocrinology outpatient departments of a regional teaching hospital in central Taiwan were recruited by consecutive sampling. Patients were assessed for psychological insulin resistance and self-management using the barriers to insulin treatment questionnaire and the partners in health scale.
      Results: A total of 222 patients with type II diabetes mellitus were recruited. Patients had an average psychological insulin resistance score of 3.14 (maximum of 8). Positive self-management was associated with insulin therapy injection by patient, fewer expectations regarding positive insulin-related outcomes, no diabetes-related complications, less fear of injection and self-testing, no hypoglycaemia within the previous year, and younger age.
      Conclusion: Insulin therapy injection by patient and no diabetes-related complications were the most common factors associated with overall self-management and with each domain of self-management in patients with type II diabetes mellitus treated with insulin therapy. Insulin therapy education should be offered to improve patients' beliefs about insulin therapy and enhance patients' ability to perform self-management.
      (© 2023 John Wiley & Sons Australia, Ltd.)
    • References:
      Adu, M. D., Malabu, U. H., Malau‐Aduli, A., & Malau‐Aduli, B. S. (2019). Enablers and barriers to effective diabetes self‐management: A multi‐national investigation. PLoS ONE, 14(6), e0217771. https://doi.org/10.1371/journal.pone.021771.
      Alomran, A. M., Almubarak, D. A., Alrashed, B. A., & Khan, A. S. (2020). Psychological insulin resistance among type 2 diabetic patients attending primary healthcare centers, Al‐Ahsa, Saudi Arabia. Journal of Family and Community Medicine, 27(3), 192–199. https://doi.org/10.4103/jfcm.JFCM_226_20.
      American Diabetes Association. (2022). Standards of medical care in diabetes‐2022 abridged for primary care providers. Clinical Diabetes, 40(1), 10–38. https://doi.org/10.2337/cd22-as01.
      Bahrmann, A., Abel, A., Zeyfang, A., Petrak, F., Kubiak, T., Hummel, J., Oster, P., & Bahrmann, P. (2014). Psychological insulin resistance in geriatric patients with diabetes mellitus. Patient Education and Counseling, 94(3), 417–422. https://doi.org/10.1016/j.pec.2013.11.010.
      Bai, X., Liu, Z., Li, Z., & Yan, D. (2018). The association between insulin therapy and depression in patients with type 2 diabetes mellitus: A meta‐analysis. BMJ Open, 8(11), e020062. https://doi.org/10.1136/bmjopen-2017-020062.
      Balogh, E. G., Perez‐Nieves, M., Cao, D., Hadjiyianni, I. I., Ashraf, N., Desai, U., Snoek, F. J., & Sturt, J. A. (2020). Key strategies for overcoming psychological insulin resistance in adults with type 2 diabetes: The UK subgroup in the EMOTION study. Diabetes Therapy, 11(8), 1735–1744. https://doi.org/10.1007/s13300-020-00856-4.
      Battersby, M., Ask, A., Reece, M., Markwick, M., & Collins, J. (2003). The Partners in Health Scale: The development and psychometric properties of a generic assessment scale for chronic condition self‐management. Australian Journal of Primary Health, 9, 41. https://doi.org/10.1071/PY03022.
      Brod, M., Kongsø, J. H., Lessard, S., & Christensen, T. L. (2009). Psychological insulin resistance: Patient beliefs and implications for diabetes management. Quality of Life Research, 18(1), 23–32. https://doi.org/10.1007/s11136-008-9419-1.
      Crutzen, S., van den Born‐Bondt, T., Denig, P., & Taxis, K. (2021). Type 2 diabetes patients' views on prevention of hypoglycaemia‐a mixed methods study investigating self‐management issues and self‐identified causes of hypoglycaemia. BMC Family Practice, 22(1), 114. https://doi.org/10.1186/s12875-021-01466-0.
      Ellis, K., Mulnier, H., & Forbes, A. (2018). Perceptions of insulin use in type 2 diabetes in primary care: A thematic synthesis. BMC Family Practice, 19(1), 70. https://doi.org/10.1186/s12875-018-0753-2.
      Faul, F., Erdfelder, E., Buchner, A., & Lang, A. G. (2009). Statistical power analyses using G*power 3.1: Tests for correlation and regression analyses. Behavior Research Methods, 41, 1149–1160. https://doi.org/10.3758/BRM.41.4.1149.
      Faul, F., Erdfelder, E., Lang, A. G., & Buchner, A. (2007). G*power 3: A flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behavior Research Methods, 39(2), 175–191. https://doi.org/10.3758/bf03193146.
      Gherman, A., Veresiu, I. A., Sassu, R. A., Schnur, J. B., Scheckner, B. L., & Montgomery, G. H. (2011). Psychological insulin resistance: A critical review of the literature. Pract Diabetes Int, 28(3), 125–128. https://doi.org/10.1002/pdi.1574.
      Holmes‐Truscott, E., Pouwer, F., & Speight, J. (2017). Assessing psychological insulin resistance in type 2 diabetes: A critical comparison of measures. Current Diabetes Reports, 17(7), 46. https://doi.org/10.1007/s11892-017-0873-4.
      International Diabetes Foundation. (2021). Diabetes now affects one in 10 adults worldwide. Retrieved from https://idf.org/news/240:diabetes-now-affects-one-in-10-adults-worldwide.html.
      Javan‐Noughabi, J., Tabatabaee, S. S., Vahedi, S., & Sharifi, T. (2022). Socio‐economic determinants of attendance at diabetes self‐management education program: Using Andersen's behavioral model. BMC Health Services Research, 22(1), 1331. https://doi.org/10.1186/s12913-022-08749-x.
      Jiang, X., Jiang, H., Li, M., Lu, Y., Liu, K., & Sun, X. (2019). The mediating role of self‐efficacy in shaping self‐management behaviors among adults with type 2 diabetes. Worldviews on Evidence‐Based Nursing, 16(2), 151–160. https://doi.org/10.1111/wvn.12354.
      Keeler, B., Meal, A., Jiwani, S. I., Gyasi‐Antwi, P., & Adams, G. G. (2021). Psychological insulin resistance in adults with type 2 diabetes mellitus. Annals of Clinical Diabetes and Endocrinology, 4(1), 1021.
      Khan, M., Hashim, M. J., King, J. K., Govender, R. D., Mustafa, H., & Al Kaabi, J. (2020). Epidemiology of type 2 diabetes—global burden of disease and forecasted trends. Journal of Epidemiology and Global Health, 10(1), 107–111. https://doi.org/10.2991/jegh.k.191028.001.
      Kosiborod, M., Gomes, M. B., Nicolucci, A., Pocock, S., Rathmann, W., Shestakova, M. V., Watada, H., Shimomura, I., Chen, H., Cid‐Ruzafa, J., Fenici, P., Hammar, N., Surmont, F., Tang, F., Khunti, K., & for The DISCOVER investigators. (2018). Vascular complications in patients with type 2 diabetes: Prevalence and associated factors in 38 countries (the DISCOVER study program). Cardiovascular Diabetology, 17(1), 150. https://doi.org/10.1186/s12933-018-0787-8.
      Langerman, C., Forbes, A., & Robert, G. (2022). The experiences of insulin use among older people with type 2 diabetes mellitus: A thematic synthesis. Primary Care Diabetes, 16(5), 614–626. https://doi.org/10.1016/j.pcd.2022.08.008.
      Lee, L. Y., Tung, H. H., Tsay, S. L., Chen, Y. C., Lee, H. H., & Zeng, Y. X. (2020). Predictors for self‐management in older adults with type 2 diabetic nephropathy. Journal of Clinical Nursing, 29(5–6), 922–931. https://doi.org/10.1111/jocn.15154.
      Li, S., Li, Y., Zhang, L., Bi, Y., Zou, Y., Liu, L., Zhang, H., Yuan, Y., Gong, W., & Zhang, Y. (2022). Impact of fear of hypoglycaemia on self‐management in patients with type 2 diabetes mellitus: Structural equation modelling. Acta Diabetologica, 59(5), 641–650. https://doi.org/10.1007/s00592-021-01839-y.
      Lim, A., & Song, Y. (2020). The role of psychological insulin resistance in diabetes self‐care management. Nursing Open, 7(3), 887–894. https://doi.org/10.1002/nop2.462.
      Liu, N. F., Brown, A. S., Folias, A. E., Younge, M. F., Guzman, S. J., Close, K. L., & Wood, R. (2017). Stigma in people with type 1 or type 2 diabetes. Clinical Diabetes, 35(1), 27–34. https://doi.org/10.2337/cd16-0020.
      Ministry of Health and Welfare. (2021). Diabetes Retrieved from https://www.hpa.gov.tw/Pages/List.aspx?nodeid=359.
      Peñarrieta, M. I., Flores‐Barrios, F., Gutiérrez‐Gómez, T., Piñones‐Martínez, S. R., Resendiz‐Gonzalez, E., & Quintero‐Valle, L. (2015). Self‐management and family support in chronic diseases. Journal of Nursing Education and Practice, 5(11), 73–80. https://doi.org/10.5430/jnep.v5n11p73.
      Petkov, J., Harvey, P., & Battersby, M. (2010). The internal consistency and construct validity of the partners in health scale: Validation of a patient rated chronic condition self‐management measure. Quality of Life Research, 19(7), 1079–1085. https://doi.org/10.1007/s11136-010-9661-1.
      Petrak, F., Stridde, E., Leverkus, F., Crispin, A. A., Forst, T., & Pfützner, A. (2007). Development and validation of a new measure to evaluate psychological resistance to insulin treatment. Diabetes Care, 30(9), 2199–2204. https://doi.org/10.2337/dc06-2042.
      Polonsky, W. H., Fisher, L., Guzman, S., Villa‐Caballero, L., & Edelman, S. V. (2005). Psychological insulin resistance in patients with type 2 diabetes: The scope of the problem. Diabetes Care, 28(10), 2543–2545. https://doi.org/10.2337/diacare.28.10.2543.
      Rita, S. L., Lubaki, F. J., Bompeka, L. F., Ogunbanjo, G. A., & Ngwala, L. P. (2019). Prevalence and determinants of psychological insulin resistance among type 2 diabetic patients in Kinshasa, Democratic Republic of Congo. Afr J Prim Health Care Fam Med, 11(1), e1–e5. https://doi.org/10.4102/phcfm.v11i1.1993.
      Saritas, S. C., Erci, B., Sahin, I., & Timocin, E. (2019). Validity study of the Turkish version of the barriers to insulin treatment questionnaire. International of Journal of Diabetes in Developing Countries, 39, 247–253. https://doi.org/10.1007/s13410-018-0670-x.
      Sharma, S. K., Kant, R., Kalra, S., & Bishnoi, R. (2020). Prevalence of primary non‐adherence with insulin and barriers to insulin initiation in patients with tpe 2 diabetes mellitus—an exploratory study in a tertiary care teaching public hospital. European Endocrinology, 16(2), 143–147. https://doi.org/10.17925/EE.2020.16.2.143.
      Song, Y., Ku, B. J., Cho, J., Jun, Y., Kim, B., & Nam, S. (2019). The prevalence of insulin refusal and psychological insulin resistance among Korean patients with type 2 diabetes mellitus. Annals of Translational Medicine, 7(23), 760. https://doi.org/10.21037/atm.2019.11.77.
      Taylor, S., Thompson, F., & McDermott, R. (2016). Barriers to insulin treatment among Australian Torres Strait islanders with poorly controlled diabetes. The Australian Journal of Rural Health, 24(6), 363–370. https://doi.org/10.1111/ajr.12315.
      Thorne, S., Paterson, B., & Russell, C. (2003). The structure of everyday self‐care decision making in chronic illness. Qualitative Health Research, 13(10), 1337–1352. https://doi.org/10.1177/1049732303258039.
      Wilkinson, A., & Whitehead, L. (2009). Evolution of the concept of self‐care and implications for nurses: A literature review. International Journal of Nursing Studies, 46(8), 1143–1147. https://doi.org/10.1016/j.ijnurstu.2008.12.011.
      Wu, F. L., Tai, H. C., & Sun, J. C. (2019). Self‐management experience of middle‐aged and older adults with type 2 diabetes: A qualitative study. Asian Nursing Research, 13(3), 209–215. https://doi.org/10.1016/j.anr.2019.06.002.
      Yu, J. H., Kim, H. Y., Kim, S. R., Ko, E., & Jin, H. Y. (2019). Factors influencing psychological insulin resistance in type 2 diabetes patients. International Journal of Nursing Practice, 25(3), e12733. https://doi.org/10.1111/ijn.12733.
      Zhang, X., Feng, H., Sharon, L., Sun, M., Smith, D., Wang, J., Ren, L., Chen, J., & Tang, S. (2017). Translation and initial psychometric evaluation of the Chinese version of the partners in health scale. Biomedical Research, 28(16), 7322–7329.
    • Grant Information:
      1-CMUBHR108-007 China Medical University Hospital; China Medical University Beigang Hospital Research Program in Taiwan
    • Contributed Indexing:
      Keywords: diabetes complications; hypoglycaemia; insulin; psychological insulin resistance; self‐management; type II diabetes mellitus
    • Accession Number:
      0 (Insulin)
      0 (Hypoglycemic Agents)
    • Publication Date:
      Date Created: 20230819 Date Completed: 20240409 Latest Revision: 20240409
    • Publication Date:
      20240409
    • Accession Number:
      10.1111/ijn.13190
    • Accession Number:
      37596927