Single Dose of an Energy Dietary Supplement with a Small Amount of Caffeine Prevents an Increase of a Low Frequency Resting State EEG in Possible Mental Fatigue.

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  • Additional Information
    • Source:
      Publisher: Elsevier Science Country of Publication: United States NLM ID: 7605074 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7544 (Electronic) Linking ISSN: 03064522 NLM ISO Abbreviation: Neuroscience Subsets: MEDLINE
    • Publication Information:
      Publication: [New York?] : Elsevier Science
      Original Publication: Oxford, Elmsford, N. Y., Pergamon Press
    • Subject Terms:
      Caffeine*/pharmacology ; Central Nervous System Stimulants*/pharmacology; Female ; Humans ; Cognition ; Dietary Supplements ; Double-Blind Method ; Electroencephalography ; Male
    • Abstract:
      Due to the increasing needs to enhance our cognitive performance, and decrease fatigue with increasing number of tasks in our everyday life, it's interesting to study whether a small amount of active substance present in dietary supplements, is enough to impact cognition. We investigated an acute effect of an energy dietary supplement containing low amount of caffeine (55 mg) and other stimulatory ingredients by means of a resting state EEG in a double blind, placebo controlled study (N = 47, 27 women). The use of a nonparametric cluster-based permutation analysis allowed us to observed a significant group × block interaction effect after 90 minutes post-ingestion (P = 0.022 cluster corrected) in the 'eyes closed' condition, i.e. an increase in normalized rsEEG power in the placebo group, which was abolished in the study group. This difference corresponded to a broad spatio-spectral cluster between around 6.5 Hz and 10.5 Hz (i.e. high theta and low alpha band) maximal over centro-temporo-parieto-occipital scalp areas. Similar trend but without significant effect was found in the 'eyes open' condition. Our results suggest that low caffeine content dietary supplementation acts as a reversal of the fatigue-related brain activity in the neural networks active in the resting state. These findings not only may help to clarify previous nonconclusive findings, but more importantly, show that an ingestion of caffeinated stimulants before neurocognitive examinations, both in research and diagnostics, should be taken into account, as they may influence cognition, even in small doses and when the effects are absent in the behavioral measures.
      Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
      (Copyright © 2023 IBRO. Published by Elsevier Ltd. All rights reserved.)
    • Contributed Indexing:
      Keywords: EEG frequency spectra; caffeine; dietary supplement; mental fatigue; resting state; stimulatory ingredients
    • Accession Number:
      3G6A5W338E (Caffeine)
      0 (Central Nervous System Stimulants)
    • Publication Date:
      Date Created: 20230712 Date Completed: 20230828 Latest Revision: 20231003
    • Publication Date:
      20231003
    • Accession Number:
      10.1016/j.neuroscience.2023.07.011
    • Accession Number:
      37437800