The role of blood flow in vessel remodeling and its regulatory mechanism during developmental angiogenesis.

Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE

Publication: Basel : Springer
Original Publication: Basel ; Boston : Birkhauser, c1997-

Zebrafish* ; Mechanotransduction, Cellular*; Animals ; Mice ; Vascular Endothelial Growth Factor A ; Cardiovascular Physiological Phenomena ; Actin Cytoskeleton

Vessel remodeling is essential for a functional and mature vascular network. According to the difference in endothelial cell (EC) behavior, we classified vessel remodeling into vessel pruning, vessel regression and vessel fusion. Vessel remodeling has been proven in various organs and species, such as the brain vasculature, subintestinal veins (SIVs), and caudal vein (CV) in zebrafish and yolk sac vessels, retina, and hyaloid vessels in mice. ECs and periendothelial cells (such as pericytes and astrocytes) contribute to vessel remodeling. EC junction remodeling and actin cytoskeleton dynamic rearrangement are indispensable for vessel pruning. More importantly, blood flow has a vital role in vessel remodeling. In recent studies, several mechanosensors, such as integrins, platelet endothelial cell adhesion molecule-1 (PECAM-1)/vascular endothelial cell (VE-cadherin)/vascular endothelial growth factor receptor 2 (VEGFR2) complex, and notch1, have been shown to contribute to mechanotransduction and vessel remodeling. In this review, we highlight the current knowledge of vessel remodeling in mouse and zebrafish models. We further underline the contribution of cellular behavior and periendothelial cells to vessel remodeling. Finally, we discuss the mechanosensory complex in ECs and the molecular mechanisms responsible for vessel remodeling.
(© 2023. The Author(s), under exclusive licence to Springer Nature Switzerland AG.)

Development. 2016 Jul 1;143(13):2249-60. (PMID: 27381223)
Dev Cell. 2015 Jan 12;32(1):109-22. (PMID: 25584797)
Circ Res. 1998 Aug 10;83(3):334-41. (PMID: 9710127)
Sci Rep. 2019 Mar 1;9(1):3263. (PMID: 30824785)
Curr Mol Med. 2018;18(1):3-14. (PMID: 29577856)
Yi Chuan. 2013 Apr;35(4):502-10. (PMID: 23659941)
Transgenic Res. 2012 Oct;21(5):1033-42. (PMID: 22427112)
Invest Ophthalmol Vis Sci. 2010 Jun;51(6):2813-26. (PMID: 20484600)
News Physiol Sci. 2002 Oct;17:197-201. (PMID: 12270956)
Clin Hemorheol Microcirc. 2016;64(4):557-563. (PMID: 27802214)
Microcirculation. 2000 Oct;7(5):317-33. (PMID: 11079250)
Dev Cell. 2015 Jul 6;34(1):5-17. (PMID: 26151903)
Biomicrofluidics. 2020 Apr 21;14(2):024115. (PMID: 32341726)
J Cell Biol. 2015 Mar 30;208(7):975-86. (PMID: 25800053)
Dev Cell. 2016 Jan 11;36(1):79-93. (PMID: 26766444)
Curr Biol. 2011 Nov 22;21(22):1942-8. (PMID: 22079115)
PLoS One. 2013 Oct 11;8(10):e75060. (PMID: 24146748)
PLoS One. 2017 May 26;12(5):e0178198. (PMID: 28552963)
EMBO J. 2001 Sep 3;20(17):4639-47. (PMID: 11532928)
Invest Ophthalmol Vis Sci. 2000 Apr;41(5):1217-28. (PMID: 10752963)
Int J Mol Sci. 2020 Oct 08;21(19):. (PMID: 33049983)
Cell. 1993 Aug 13;74(3):453-62. (PMID: 8348612)
Anat Rec A Discov Mol Cell Evol Biol. 2003 May;272(1):403-14. (PMID: 12704698)
Arterioscler Thromb Vasc Biol. 2018 Sep;38(9):2174-2183. (PMID: 29930007)
Cell Mol Life Sci. 2021 Apr;78(7):3247-3264. (PMID: 33783563)
Circ Res. 2000 Oct 13;87(8):683-9. (PMID: 11029404)
J Cell Biol. 2002 Aug 19;158(4):773-85. (PMID: 12177047)
J Histochem Cytochem. 1999 Nov;47(11):1351-6. (PMID: 10544208)
Blood. 2011 Jun 16;117(24):6728-37. (PMID: 21498671)
Dev Dyn. 2019 Dec;248(12):1243-1256. (PMID: 31566834)
PLoS One. 2012;7(1):e30203. (PMID: 22272305)
Front Mol Neurosci. 2018 Jun 28;11:222. (PMID: 30002618)
Microcirculation. 2010 Jul;17(5):348-57. (PMID: 20618692)
Development. 2014 Apr;141(8):1757-66. (PMID: 24715464)
Prog Retin Eye Res. 2019 May;70:110-133. (PMID: 30513356)
Development. 2007 Sep;134(18):3317-26. (PMID: 17720695)
Development. 2013 Oct;140(19):4041-50. (PMID: 24004946)
Cell. 2009 Oct 16;139(2):285-98. (PMID: 19837032)
Vascul Pharmacol. 2014 Nov;63(2):97-104. (PMID: 25464152)
Neuron. 2017 Dec 6;96(5):1055-1069.e6. (PMID: 29154126)
Circ Res. 2010 Oct 15;107(8):943-52. (PMID: 20947863)
Development. 2007 Dec;134(24):4449-58. (PMID: 18039971)
Development. 2008 Nov;135(22):3655-64. (PMID: 18842812)
PLoS Genet. 2021 Jul 28;17(7):e1009690. (PMID: 34319989)
Development. 2019 Apr 17;146(8):. (PMID: 30910827)
Research (Wash D C). 2022 Apr 4;2022:9839368. (PMID: 35465346)
Bull Math Biol. 1984;46(1):127-37. (PMID: 6713148)
Eur J Cell Biol. 2011 May;90(5):440-8. (PMID: 21354650)
Elife. 2016 Feb 04;5:e07727. (PMID: 26845523)
PLoS Biol. 2012;10(8):e1001374. (PMID: 22904685)
Ann Anat. 1999 Dec;181(6):555-60. (PMID: 10609053)
PLoS Biol. 2015 Apr 17;13(4):e1002126. (PMID: 25884426)
Nat Commun. 2016 Jun 01;7:11805. (PMID: 27248505)
Dev Cell. 2010 Jun 15;18(6):938-49. (PMID: 20627076)
Mol Cell Neurosci. 2008 Jan;37(1):85-95. (PMID: 17931883)
Development. 2018 Jun 14;145(12):. (PMID: 29777010)
Mol Biol Cell. 2016 Jan 1;27(1):7-11. (PMID: 26715421)
Elife. 2015 Feb 02;4:. (PMID: 25643397)
Curr Biol. 2017 Jul 24;27(14):2219-2225.e5. (PMID: 28712573)
J Cell Biol. 2011 Nov 14;195(4):689-701. (PMID: 22084310)
Nature. 2005 Sep 15;437(7057):417-21. (PMID: 16163358)
PLoS Biol. 2015 May 15;13(5):e1002148. (PMID: 25978860)
Cell. 2004 Mar 19;116(6):883-95. (PMID: 15035989)
J Ophthalmol. 2018 Jul 05;2018:3565292. (PMID: 30116629)
Dev Dyn. 2010 Feb;239(2):398-406. (PMID: 19918756)
J Biomech. 2019 Apr 18;87:83-92. (PMID: 30850176)
Nature. 2017 Dec 14;552(7684):258-262. (PMID: 29160307)
Curr Top Dev Biol. 2010;92:277-309. (PMID: 20816399)
Nat Commun. 2018 Dec 14;9(1):5314. (PMID: 30552331)
Dev Cell. 2015 Jan 12;32(1):123-32. (PMID: 25584798)
PLoS Biol. 2015 May 14;13(5):e1002163. (PMID: 25974400)
Cell. 2012 Jun 8;149(6):1192-205. (PMID: 22682243)
Biomaterials. 2017 Sep;140:45-57. (PMID: 28624707)
Circulation. 2020 Aug 18;142(7):688-704. (PMID: 32466671)
Development. 1998 May;125(9):1591-8. (PMID: 9521897)
Development. 1999 Apr;126(7):1407-15. (PMID: 10068634)
Dev Biol. 2008 Apr 15;316(2):312-22. (PMID: 18342303)
PLoS Comput Biol. 2021 Feb 4;17(2):e1007715. (PMID: 33539345)
Front Physiol. 2021 Feb 25;12:639645. (PMID: 33716786)
Cell Mol Life Sci. 2017 Feb;74(4):731-746. (PMID: 27652381)
Development. 2013 Jul;140(14):3051-61. (PMID: 23785053)
Curr Biol. 2013 Jun 3;23(11):1024-30. (PMID: 23684974)
J Cell Biol. 2003 Apr 28;161(2):429-39. (PMID: 12719476)
J Cell Sci. 2016 Mar 15;129(6):1093-100. (PMID: 26919980)
Blood. 2012 Nov 8;120(19):4104-15. (PMID: 23007403)
J Clin Invest. 1996 Dec 1;98(11):2623-31. (PMID: 8958227)
Prog Retin Eye Res. 2018 Mar;63:1-19. (PMID: 29129724)
Arterioscler Thromb Vasc Biol. 2013 Dec;33(12):2818-29. (PMID: 24135023)
Dev Cell. 2009 Jan;16(1):70-82. (PMID: 19154719)
Arterioscler Thromb Vasc Biol. 2009 Jul;29(7):1067-73. (PMID: 19390054)
Yi Chuan. 2012 Sep;34(9):1123-32. (PMID: 23017453)
Cell Res. 2019 Nov;29(11):895-910. (PMID: 31501519)
Physiology (Bethesda). 2014 Nov;29(6):446-55. (PMID: 25362638)
Development. 1996 Dec;122(12):3929-38. (PMID: 9012513)
Invest Ophthalmol Vis Sci. 2012 Sep 21;53(10):6495-503. (PMID: 22930727)
Proc Natl Acad Sci U S A. 2020 May 5;117(18):9896-9905. (PMID: 32321834)
Nature. 2005 Sep 15;437(7057):426-31. (PMID: 16163360)
Dev Dyn. 2008 Oct;237(10):2918-25. (PMID: 18816835)
J Cell Biol. 2003 Sep 15;162(6):1111-22. (PMID: 12975353)
Development. 2016 Aug 15;143(16):2973-82. (PMID: 27471260)
J Clin Invest. 2019 Dec 2;129(12):5092-5107. (PMID: 31454332)
Dev Dyn. 2005 Sep;234(1):36-47. (PMID: 16003775)
J Clin Invest. 1999 Jan;103(2):159-65. (PMID: 9916127)
Cell Tissue Res. 2014 Mar;355(3):529-43. (PMID: 24643678)
Invest Ophthalmol Vis Sci. 2005 Sep;46(9):3372-82. (PMID: 16123442)
J Cell Physiol. 1995 Apr;163(1):179-93. (PMID: 7534769)

12032007 National Natural Science Foundation of China; 31971242 National Natural Science Foundation of China

Keywords: EC rearrangement; Hemodynamics; Vessel pruning; Wnt signaling; Zebrafish

0 (Vascular Endothelial Growth Factor A)

Date Created: 20230523 Date Completed: 20230525 Latest Revision: 20240516

20240516

PMC11072276

10.1007/s00018-023-04801-z

37221410