Pneumonia During the COVID-19 Pandemic in Hubei Province, China: a Case Report of Mucormycosis.

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
Read More Add to Saved list
  • Additional Information
    • Source:
      Publisher: Clinical Laboratory Publications Country of Publication: Germany NLM ID: 9705611 Publication Model: Print Cited Medium: Internet ISSN: 1433-6510 (Print) Linking ISSN: 14336510 NLM ISO Abbreviation: Clin Lab Subsets: MEDLINE
    • Publication Information:
      Publication: 2010- : Mainz : Clinical Laboratory Publications
      Original Publication: Heidelberg : Verlag Klinisches Labor, [1997-
    • Subject Terms:
      Mucormycosis*/diagnosis ; Mucormycosis*/epidemiology ; COVID-19* ; Pneumonia* ; Invasive Fungal Infections*; Humans ; Pandemics ; China/epidemiology ; Antiviral Agents ; Bronchoalveolar Lavage Fluid ; High-Throughput Nucleotide Sequencing
    • Abstract:
      Background: Mucor infection cannot be ignored in patients with pulmonary shadowing with cavitation. This paper reports a case of mucormycosis during the COVID-19 pandemic in Hubei Province, China.
      Methods: An anesthesiology doctor was initially diagnosed as COVID-19 due to changes in lung imaging. After anti-infective, anti-viral, and symptomatic supportive treatment, some of symptoms were relieved. But some symptoms -'chest pain and discomfort', accompanied by chest sulking and short breath after activities, did not ease. At last, Lichtheimia ramose was detected later by metagenomic next generation sequencing (mNGS) in the bronchoalveolar lavage fluid (BALF).
      Results: After adjusting amphotericin B for anti-infective treatment, the patient's infection lesions were shrunk and the symptoms were significantly relieved.
      Conclusions: The diagnosis of invasive fungal infections is very difficult, and mNGS can make an accurate pathogenic diagnosis of invasive fungal diseases for the clinic and provide a basis for clinical treatment.
    • Accession Number:
      0 (Antiviral Agents)
    • Publication Date:
      Date Created: 20230505 Date Completed: 20230508 Latest Revision: 20230508
    • Publication Date:
      20240829
    • Accession Number:
      10.7754/Clin.Lab.2022.220905
    • Accession Number:
      37145069