Underrepresentation of racial and ethnic minorities in cascade testing for hereditary cancer syndromes.

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
Read More Add to Saved list
  • Additional Information
    • Source:
      Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9302235 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5438 (Electronic) Linking ISSN: 10184813 NLM ISO Abbreviation: Eur J Hum Genet Subsets: MEDLINE
    • Publication Information:
      Publication: <2003->: London : Nature Publishing Group
      Original Publication: Basel ; New York : Karger, [1992-
    • Subject Terms:
      Ethnic and Racial Minorities* ; Neoplastic Syndromes, Hereditary*/diagnosis ; Neoplastic Syndromes, Hereditary*/genetics; Humans ; Ethnicity/genetics ; Racial Groups ; Minority Groups
    • References:
      Makhnoon S, Tran G, Levin B, Mattie KD, Dreyer B, Volk RJ, et al. Uptake of cancer risk management strategies among women who undergo cascade genetic testing for breast cancer susceptibility genes. Cancer. 2021;127:3605–13. https://doi.org/10.1002/cncr.33668. (PMID: 10.1002/cncr.3366834157779)
      de Jong AE, Hendriks YM, Kleibeuker JH, de Boer SY, Cats A, Griffioen G, et al. Decrease in mortality in Lynch syndrome families because of surveillance. Gastroenterology 2006;130:665–71. https://doi.org/10.1053/j.gastro.2005.11.032. (PMID: 10.1053/j.gastro.2005.11.03216530507)
      Center for Disease Control and Prevention: Tier 1 Genomic Applications Toolkit for Public Health Departments. 2019. https://www.cdc.gov/genomics/implementation/toolkit/ . Accessed 12 Sep 2019.
      Offit K, Tkachuk KA, Stadler ZK, Walsh MF, Diaz-Zabala H, Levin JD, et al. Cascading after peridiagnostic cancer genetic testing: an alternative to population-based screening. Journal of Clinical Oncology. 2020:JCO1902010. https://doi.org/10.1200/JCO.19.02010.
      Frey MK, Ahsan MD, Bergeron H, Lin J, Li X, Fowlkes RK, et al. Cascade testing for hereditary cancer syndromes: should we move toward direct relative contact? A systematic review and meta-analysis. Journal of Clinical Oncology.. 2022:JCO2200303. https://doi.org/10.1200/JCO.22.00303.
      Levy DE, Byfield SD, Comstock CB, Garber JE, Syngal S, Crown WH, et al. Underutilization of BRCA1/2 testing to guide breast cancer treatment: black and Hispanic women particularly at risk. Genet Med. 2011;13:349–55. https://doi.org/10.1097/GIM.0b013e3182091ba4. (PMID: 10.1097/GIM.0b013e3182091ba4213583363604880)
      Lin J, Sharaf RN, Saganty R, Ahsan D, Feit J, Khoury A, et al. Achieving universal genetic assessment for women with ovarian cancer: are we there yet? A systematic review and meta-analysis. Gynecol Oncol. 2021;162:506–16. https://doi.org/10.1016/j.ygyno.2021.05.011.
      Lemke AA, Esplin ED, Goldenberg AJ, Gonzaga-Jauregui C, Hanchard NA, Harris-Wai J, et al. Addressing underrepresentation in genomics research through community engagement. Am J Hum Genet. 2022;109:1563–71. https://doi.org/10.1016/j.ajhg.2022.08.005. (PMID: 10.1016/j.ajhg.2022.08.005360552089502069)
    • Grant Information:
      K07 CA216326 United States CA NCI NIH HHS; KL2 TR002385 United States TR NCATS NIH HHS; R01 CA211723 United States CA NCI NIH HHS; UL1 TR002384 United States TR NCATS NIH HHS
    • Publication Date:
      Date Created: 20230428 Date Completed: 20230710 Latest Revision: 20240425
    • Publication Date:
      20250114
    • Accession Number:
      PMC10325970
    • Accession Number:
      10.1038/s41431-023-01364-2
    • Accession Number:
      37117326