Splenic surprise in a case of renal cell carcinoma: Unusual case or association?

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  • Additional Information
    • Source:
      Publisher: Medknow Publications Country of Publication: India NLM ID: 2985196R Publication Model: Print Cited Medium: Internet ISSN: 0972-2823 (Electronic) Linking ISSN: 00223859 NLM ISO Abbreviation: J Postgrad Med Subsets: MEDLINE
    • Publication Information:
      Publication: Mumbai : Medknow Publications
      Original Publication: Bombay, India.
    • Subject Terms:
      Carcinoma, Renal Cell*/complications ; Carcinoma, Renal Cell*/surgery ; Splenic Neoplasms*/complications ; Splenic Neoplasms*/surgery ; Splenic Neoplasms*/diagnosis ; Hemangioma*/complications ; Hemangioma*/diagnosis ; Hemangioma*/pathology ; Kidney Neoplasms*; Humans
    • Abstract:
      Littoral cell angioma (LCA) is a rare benign tumor originating exclusively from the venous sinus lining cells of the splenic red pulp. These cells are unique in having a distinctive hybrid endothelial/histiocytic phenotype. Also, there are reports of the association of LCA with internal malignancies. We present a case report highlighting an unusual association of LCA with conventional renal cell carcinoma (RCC), masquerading as a metastatic lesion. Knowledge of such an association is necessary to avoid misdiagnosis and prevent potential overtreatment.
      Competing Interests: None
    • Comments:
      Comment in: J Postgrad Med. 2023 Apr-Jun;69(2):70-71. (PMID: 36930543)
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    • Contributed Indexing:
      Keywords: Littoral cell angioma; red pulp; renal cell carcinoma; spleen
    • Subject Terms:
      Littoral cell angioma of the spleen
    • Publication Date:
      Date Created: 20230309 Date Completed: 20230417 Latest Revision: 20230614
    • Publication Date:
      20230614
    • Accession Number:
      PMC10259435
    • Accession Number:
      10.4103/jpgm.jpgm_285_22
    • Accession Number:
      36891941