Palaeogenomics of Upper Palaeolithic to Neolithic European hunter-gatherers.

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Author(s): Posth C;Posth C;Posth C;Posth C; Yu H; Yu H; Yu H; Ghalichi A; Ghalichi A; Rougier H; Rougier H; Rougier H; Crevecoeur I; Crevecoeur I; Huang Y; Huang Y; Ringbauer H; Ringbauer H; Rohrlach AB; Rohrlach AB; Rohrlach AB; Nägele K; Nägele K; Villalba-Mouco V; Villalba-Mouco V; Villalba-Mouco V; Radzeviciute R; Radzeviciute R; Radzeviciute R; Ferraz T; Ferraz T; Stoessel A; Stoessel A; Stoessel A; Tukhbatova R; Tukhbatova R; Tukhbatova R; Drucker DG; Drucker DG; Lari M; Lari M; Modi A; Modi A; Vai S; Vai S; Saupe T; Saupe T; Scheib CL; Scheib CL; Scheib CL; Catalano G; Catalano G; Pagani L; Pagani L; Pagani L; Talamo S; Talamo S; Talamo S; Fewlass H; Fewlass H; Klaric L; Klaric L; Morala A; Morala A; Morala A; Rué M; Rué M; Rué M; Madelaine S; Madelaine S; Madelaine S; Crépin L; Crépin L; Caverne JB; Caverne JB; Caverne JB; Bocaege E; Bocaege E; Ricci S; Ricci S; Ricci S; Boschin F; Boschin F; Boschin F; Boschin F; Bayle P; Bayle P; Maureille B; Maureille B; Le Brun-Ricalens F; Le Brun-Ricalens F; Bordes JG; Bordes JG; Oxilia G; Oxilia G; Bortolini E; Bortolini E; Bortolini E; Bignon-Lau O; Bignon-Lau O; Debout G; Debout G; Orliac M; Orliac M; Zazzo A; Zazzo A; Sparacello V; Sparacello V; Starnini E; Starnini E; Sineo L; Sineo L; van der Plicht J; van der Plicht J; Pecqueur L; Pecqueur L; Pecqueur L; Merceron G; Merceron G; Garcia G; Garcia G; Garcia G; Leuvrey JM; Leuvrey JM; Garcia CB; Garcia CB; Gómez-Olivencia A; Gómez-Olivencia A; Gómez-Olivencia A; Gómez-Olivencia A; Połtowicz-Bobak M; Połtowicz-Bobak M; Bobak D; Bobak D; Le Luyer M; Le Luyer M; Le Luyer M; Le Luyer M; Storm P; Storm P; Hoffmann C; Hoffmann C; Kabaciński J; Kabaciński J; Filimonova T; Filimonova T; Shnaider S; Shnaider S; Berezina N; Berezina N; González-Rabanal B; González-Rabanal B; González Morales MR; González Morales MR; Marín-Arroyo AB; Marín-Arroyo AB; López B; López B; Alonso-Llamazares C; Alonso-Llamazares C; Ronchitelli A; Ronchitelli A; Polet C; Polet C; Jadin I; Jadin I; Cauwe N; Cauwe N; Soler J; Soler J; Coromina N; Coromina N; Rufí I; Rufí I; Cottiaux R; Cottiaux R; Clark G; Clark G; Straus LG; Straus LG; Straus LG; Julien MA; Julien MA; Julien MA; Renhart S; Renhart S; Talaa D; Talaa D; Benazzi S; Benazzi S; Romandini M; Romandini M; Romandini M; Romandini M; Amkreutz L; Amkreutz L; Amkreutz L; Bocherens H; Bocherens H; Bocherens H; Wißing C; Wißing C; Wißing C; Villotte S; Villotte S; Villotte S; Villotte S; de Pablo JF; de Pablo JF; Gómez-Puche M; Gómez-Puche M; Esquembre-Bebia MA; Esquembre-Bebia MA; Bodu P; Bodu P; Smits L; Smits L; Souffi B; Souffi B; Souffi B; Jankauskas R; Jankauskas R; Kozakaitė J; Kozakaitė J; Cupillard C; Cupillard C; Cupillard C; Benthien H; Benthien H; Wehrberger K; Wehrberger K; Schmitz RW; Schmitz RW; Feine SC; Feine SC; Feine SC; Schüler T; Schüler T; Thevenet C; Thevenet C; Grigorescu D; Grigorescu D; Grigorescu D; Lüth F; Lüth F; Kotula A; Kotula A; Piezonka H; Piezonka H; Schopper F; Schopper F; Svoboda J; Svoboda J; Sázelová S; Sázelová S; Chizhevsky A; Chizhevsky A; Khokhlov A; Khokhlov A; Conard NJ; Conard NJ; Conard NJ; Valentin F; Valentin F; Harvati K; Harvati K; Harvati K; Harvati K; Semal P; Semal P; Jungklaus B; Jungklaus B; Suvorov A; Suvorov A; Schulting R; Schulting R; Moiseyev V; Moiseyev V; Mannermaa K; Mannermaa K; Buzhilova A; Buzhilova A; Terberger T; Terberger T; Terberger T; Caramelli D; Caramelli D; Altena E; Altena E; Haak W; Haak W; Krause J; Krause J
Source:
Nature [Nature] 2023 Mar; Vol. 615 (7950), pp. 117-126. Date of Electronic Publication: 2023 Mar 01.
Publication Type:
Journal Article; Research Support, Non-U.S. Gov't
Language:
English

Additional Information
- Source:
  Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
- Publication Information:
  Publication: Basingstoke : Nature Publishing Group
  Original Publication: London, Macmillan Journals ltd.
- Subject Terms:
  Archaeology* ; Genomics* ; Hunting* ; Paleontology* ; Human Genetics* ; Genome, Human*/genetics; Humans ; Europe/ethnology ; Gene Pool ; History, Ancient
- Abstract:
  Modern humans have populated Europe for more than 45,000 years ^1,2 . Our knowledge of the genetic relatedness and structure of ancient hunter-gatherers is however limited, owing to the scarceness and poor molecular preservation of human remains from that period ³ . Here we analyse 356 ancient hunter-gatherer genomes, including new genomic data for 116 individuals from 14 countries in western and central Eurasia, spanning between 35,000 and 5,000 years ago. We identify a genetic ancestry profile in individuals associated with Upper Palaeolithic Gravettian assemblages from western Europe that is distinct from contemporaneous groups related to this archaeological culture in central and southern Europe ⁴ , but resembles that of preceding individuals associated with the Aurignacian culture. This ancestry profile survived during the Last Glacial Maximum (25,000 to 19,000 years ago) in human populations from southwestern Europe associated with the Solutrean culture, and with the following Magdalenian culture that re-expanded northeastward after the Last Glacial Maximum. Conversely, we reveal a genetic turnover in southern Europe suggesting a local replacement of human groups around the time of the Last Glacial Maximum, accompanied by a north-to-south dispersal of populations associated with the Epigravettian culture. From at least 14,000 years ago, an ancestry related to this culture spread from the south across the rest of Europe, largely replacing the Magdalenian-associated gene pool. After a period of limited admixture that spanned the beginning of the Mesolithic, we find genetic interactions between western and eastern European hunter-gatherers, who were also characterized by marked differences in phenotypically relevant variants.
  (© 2023. The Author(s).)
- Comments:
  Comment in: Nature. 2023 Mar;615(7950):41-42. (PMID: 36859577)
  Comment in: Nat Rev Genet. 2023 May;24(5):271. (PMID: 36914776)
  Erratum in: Nature. 2023 Apr;616(7956):E5. (PMID: 36949207)
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- Publication Date:
  Date Created: 20230301 Date Completed: 20230303 Latest Revision: 20240229
- Publication Date:
  20240229
- Accession Number:
  PMC9977688
- Accession Number:
  10.1038/s41586-023-05726-0
- Accession Number:
  36859578

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