Anatomsko-histološke karakteristike vagine rekonstruisane metodom McIndoe. (Serbian).

Anatomic and histological characteristics of vagina reconstructed by McIndoe method. (English)

VAGINAL surgery; VAGINA abnormalities; HUMAN abnormalities; VAGINAL diseases; PLASTIC surgery

Background/Aim. Congenital absence of vagina is known from ancient times of Greek. According to the literature data, incidence is 1/4 000 to 1/20 000. Treatment of this anomaly includes non-operative and operative procedures. McIndoe procedure uses split skin graft by Thiersch. The aim of this study was to establish anatomic and histological characteristics of vagina reconstructed by McIndoe method in Mayer Küster-Rockitansky Hauser (MKRH) syndrome and compare them with normal vagina. Methods. The study included 21 patients of 18 and more years with congenital anomaly known as aplasio vaginae within the Mayer Küster-Rockitansky Hauser syndrome. The patients were operated on by the plastic surgeon using the McIndoe method. The study was a retrospective review of the data from the history of the disease, objective and gynecological examination and cytological analysis of native preparations of vaginal stain (Papanicolau). Comparatively, 21 females of 18 and more years with normal vaginas were also studed. All the subjects were divided into the groups R (reconstructed) and C (control) and the subgroups according to age up to 30 years (1 R, 1C), from 30 to 50 (2R, 2C), and over 50 (3R, 3C). Statistical data processing was performed by using the Student's t-test and Mann-Writney U-test. A value of p < 0.05 was considered statistically significant. Results. The results show that there are differences in the depth and the wideness of reconstructed vagina, but the obtained values are still in the range of normal ones. Cytological differences between a reconstructed and the normal vagina were found. Conclusion. A reconstructed vagina is smaller than the normal one regarding depth and width, but within the range of normal values. A split skin graft used in the reconstruction, keeps its own cytological, i.e. histological and, so, biological characteristics. [ABSTRACT FROM AUTHOR]

Uvod/Cilj. Kongenitalna anomalija aplasio vaginas poznata je još iz doba stare Grčke. Prema podacima iz literature in-cidencija ove anomalije je od 1/4 000 do 1/20 000. Leče-nje se izvodi neoperativnim i operativnim tehnikama. McIndoe metodą koristi autotransplantat kože tipą Thiersch za rekonstrukcijų. Cilj ovog rada bio je da se utvrde ana-tomsko-histološke karakteristike vagine rekonstruisane metodom McIndoe u okviru sindromą Mayer Kūster-Rockitansky Hauser (MKRH) i uporede sa karakteristika-ma normalne vagine. Metode. Studijom je obuhvačena 21 bolesnica, starosti 18 god. i više sa kongenitalnom anomalijom aplasio vaginas u okviru sindromą Mayer Kūster-Rockitansky Hauser kod kojih je učinjena rekonstrukcija vagine metodom McIndoe od strane plastičnog hirurga (grupa R). Ispitivanje je obuhvatilo retrospektivni pregled podataka iz istorija bolesti, objektivni i ginekološki pregled uz merenje dubinę i širine vagine, histološki pregled i citološku analizu nativnih preparatą vaginalnog brisa (Papa-nikolau). Uporedo je ispitivana i 21 osoba ženskog pola starosti 18 godina i više sa normalnom vaginom (grupa K). Sve ispitanice, osim u grupe R i K, svrstane su prema starosti u podgrupe do 30 godina (IR i IK), od 30 do 50 godina (2R i 2K) i preko 50 godina (3R i 3K). Za statističku obradu podataka koriščeni su Studentov t tęst i Mann Writney U tęst. Vrednost p < 0,05 smatrana je statistički značajnom. Rezultati. Pokazano je da postoje razlike u dubini i širmi rekonstruisane vagine, ali se one nalaze u opsegu normalnih vrednosti. Utvrdene su citološke razlike izmedu rekonstruisane i normalne vagine. Zaključak. Re-konstruisana vagina je u pogledu dubinę i širine manja od normalne, ali se nalazi u opsegu normalnih vrednosti. Autotransplantat kože koji je koriščen za rekonstrukcijų zadržava svoje citološke tj. histološke, a time i biološke karakteristike. [ABSTRACT FROM AUTHOR]

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