APPLICATION OF BIOLOGICAL TISSUE REPAIR STIMULATOR AND SEALANTS IN SURGICAL TREATMENT OF BRONCHOPLEURAL FISTULAS.

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  • Additional Information
    • Source:
      Publisher: Assot︠s︡iat︠s︡ii︠a︡ delovoĭ pressy Gruzii Country of Publication: Georgia (Republic) NLM ID: 101218222 Publication Model: Print Cited Medium: Internet ISSN: 1512-0112 (Print) Linking ISSN: 15120112 NLM ISO Abbreviation: Georgian Med News Subsets: MEDLINE
    • Publication Information:
      Original Publication: Tbilisi : Nʹi︠u︡-Ĭork : Assot︠s︡iat︠s︡ii︠a︡ delovoĭ pressy Gruzii ; International Academy of Science, Education, Industry & Arts
    • Subject Terms:
      Bronchial Fistula*/surgery ; Bronchial Fistula*/etiology ; Pleural Diseases*/surgery ; Pleural Diseases*/etiology ; Empyema, Pleural*/drug therapy ; Empyema, Pleural*/etiology ; Empyema, Pleural*/surgery; Humans ; Fibrin Tissue Adhesive/therapeutic use
    • Abstract:
      The aim of the study was to increase the effectiveness of surgical treatment of patients with pleural empyema complicated by the development of bronchopleural fistula due to the personification of the surgical approach to treatment. The cohort observation group consisted of 136 patients who were treated at the I. V. Davydovsky State Clinical Hospital No. 23 for pleural empyema complicated by bronchopleural fistula. The main group included patients in whom a biological stimulator of local tissue repair (BSRMT) was used to treat EP with BPS. The comparison group included patients who used the installation of a valvular broncho blocker for the treatment of EP with BPS. Results: the effectiveness of the use of fibrin glue ranged from 57.1% to 86.4%, depending on the etiology of the EP. The effectiveness of broncho location ranges from 80% to 84.2%. The greatest effectiveness was observed with the simultaneous use of fibrin glue and broncho blocking. The use of biological stimulants based on fibrinogen and growth factors may be effective in the treatment of various nosologies of the thoracic profile. Fibrin glue, obtained from its own blood plasma, has good adhesion indicators, is biologically inert, in addition, it has the property of stimulating repair, which is extremely important in the treatment of such pathology as bronchopleural fistulas. However, the issue of the use of fibrin glue and other sealants requires further study.
    • Accession Number:
      0 (Fibrin Tissue Adhesive)
    • Publication Date:
      Date Created: 20230213 Date Completed: 20230215 Latest Revision: 20230215
    • Publication Date:
      20230215
    • Accession Number:
      36780617