Are brain MRI abnormalities associated with the semiology of functional seizures?

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  • Additional Information
    • Source:
      Publisher: John Wiley & Sons Country of Publication: United States NLM ID: 101570837 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2162-3279 (Electronic) NLM ISO Abbreviation: Brain Behav Subsets: MEDLINE
    • Publication Information:
      Original Publication: Hoboken, NJ : John Wiley & Sons
    • Subject Terms:
      Electroencephalography* ; Brain Diseases*; Humans ; Seizures/diagnosis ; Magnetic Resonance Imaging ; Brain/diagnostic imaging ; Retrospective Studies
    • Abstract:
      Purpose: To investigate whether radiologically apparent brain magnetic resonance imaging (MRI) abnormalities are associated with the functional seizure (FS) semiology.
      Methods: All patients with a diagnosis of FS at the epilepsy centers at Shiraz University of Medical Sciences, Iran; Aichi Medical University Hospital, Japan; University of Michigan, USA; University of California, Los Angeles, USA; Emory University School of Medicine, USA; and Hospital el Cruce, Argentina, were studied.
      Results: One hundred patients were included; 77 (77%) had motor functional seizures. Lobar location of brain abnormality did not have an association with the semiology (p = .83). There was no significant difference between ictal behaviors in patients with frontal or parietal lesions compared to those with temporal or occipital lesions.
      Conclusion: There were no associations between functional seizure ictal behaviors and locations of the radiologically apparent brain MRI abnormalities. Further studies are needed to evaluate the underpinnings of varying behaviors in FS.
      (© 2023 The Authors. Brain and Behavior published by Wiley Periodicals LLC.)
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    • Grant Information:
      R25 NS065723 United States NS NINDS NIH HHS; R25 NS089450 United States NS NINDS NIH HHS
    • Contributed Indexing:
      Keywords: magnetic resonance imaging (MRI); neuropsychiatrics; psychiatric disorders
    • Publication Date:
      Date Created: 20230110 Date Completed: 20230216 Latest Revision: 20230228
    • Publication Date:
      20231215
    • Accession Number:
      PMC9927836
    • Accession Number:
      10.1002/brb3.2882
    • Accession Number:
      36624686