The transition to parenthood, opportunity to drink, drinking, and alcohol use disorder.

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  • Additional Information
    • Source:
      Publisher: Elsevier Country of Publication: Ireland NLM ID: 7513587 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0046 (Electronic) Linking ISSN: 03768716 NLM ISO Abbreviation: Drug Alcohol Depend Subsets: MEDLINE
    • Publication Information:
      Publication: Limerick : Elsevier
      Original Publication: Lausanne, Elsevier Sequoia.
    • Subject Terms:
    • Abstract:
      Background: This study used life histories from a setting of near universal marriage and childbearing (Nepal) to identify associations between both marital transitions and the transition into parenthood and alcohol use and disorder (AUD).
      Methods: A retrospective, cross-sectional survey using life history calendars documented lifetime marital and childbearing histories of 4876 men and 5742 women aged 15-59 in 2016-18. The clinically validated, Nepal-specific Composite International Diagnostic Interview assessed first alcohol use opportunity, use, and disorder.
      Results: Being never married increased the odds of having the opportunity to drink for men (OR=1.30, 95% CI=1.14 - 1.48, p < 0.001) and women (OR=1.24, 95% CI=1.08 - 1.43, p = 0.003) compared to being married. While men were never married, widowed, or divorced they were at a greater risk of developing AUD. The transition to parenthood significantly increased the odds of AUD onset for men (OR=1.71, 95% CI=1.12 - 2.61, p = 0.013), independent of marital transitions. For women in this setting, becoming divorced increased the odds of having their first drink (OR=1.77, 95% CI=1.14 - 2.75, p = 0.011). Giving birth to a first child also increased the odds of first opportunity to drink for women (OR=1.30, 95% CI=1.07 - 1.57, p = 0.008).
      Conclusions: We found associations between marital transitions and AUD that are consistent with findings worldwide. In this setting of near universal childbearing, the transition into fatherhood increased the odds of postpartum AUD among men.
      Competing Interests: Conflict of Interest Axinn, Ghimire, Cole, and Smoller report support from the National Institute of Mental Health (grant number R01MH110872); Axinn and Ghimire report support from a Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) center grant to the Population Studies Center (PSC) at the University of Michigan (grant number P2CHD041028); and Banchoff reports support from an NICHD training grant to the PSC at the University of Michigan (grant number T32HD007339) during the conduct of the study. Ghimire is also the Director of the Institute for Social and Environmental Research–Nepal (ISER-N) that collected the data for the research reported here. Ghimire’s conflict of interest management plan is approved and monitored by the Regents of the University of Michigan. Dr. Smoller is PI of a collaborative study of the genetics of depression and bipolar disorder sponsored by 23andMe for which 23andMe provides analysis time as in-kind support but no payments.
      (Copyright © 2022 Elsevier B.V. All rights reserved.)
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    • Grant Information:
      P2C HD041028 United States HD NICHD NIH HHS; R01 HD099135 United States HD NICHD NIH HHS; R01 MH110872 United States MH NIMH NIH HHS; T32 HD007339 United States HD NICHD NIH HHS
    • Contributed Indexing:
      Keywords: Alcohol use disorders; Alcohol use transitions; Marital experience; Parenthood
    • Publication Date:
      Date Created: 20221124 Date Completed: 20221216 Latest Revision: 20240617
    • Publication Date:
      20240617
    • Accession Number:
      PMC10314724
    • Accession Number:
      10.1016/j.drugalcdep.2022.109697
    • Accession Number:
      36423463