CCN Proteins (Cellular Communication Network Factors): Expanding Their Repertoire Toward a New Concept.

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  • Author(s): Takigawa M;Takigawa M
  • Source:
    Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2023; Vol. 2582, pp. 1-10.
  • Publication Type:
    Journal Article; Research Support, Non-U.S. Gov't
  • Language:
    English
  • Additional Information
    • Source:
      Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029 (Electronic) Linking ISSN: 10643745 NLM ISO Abbreviation: Methods Mol Biol Subsets: MEDLINE
    • Publication Information:
      Publication: Totowa, NJ : Humana Press
      Original Publication: Clifton, N.J. : Humana Press,
    • Subject Terms:
      CCN Intercellular Signaling Proteins*/genetics ; CCN Intercellular Signaling Proteins*/metabolism ; Cell Communication*; Signal Transduction ; Extracellular Matrix Proteins/metabolism
    • Abstract:
      I herein report the general structures and functions of CCN proteins and possible molecular mechanisms involved in the unique biological actions of this family of intercellular signaling regulators, which are considered matricellular proteins and were once referred to as "signal conductors" but have recently been renamed "Cellular Communication Network Factors." Their repertoire of functions beyond their role as matricellular proteins is also described to aid in future studies. Advanced research concerning their relevance to pathology is briefly introduced as well. The information provided in this chapter is expected to be useful for readers of subsequent chapters.
      (© 2023. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.)
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    • Contributed Indexing:
      Keywords: Binding partner; CCN family; Cellular communication network factor; Intercellular signaling; Matricellular protein; Structure
    • Accession Number:
      0 (CCN Intercellular Signaling Proteins)
      0 (Extracellular Matrix Proteins)
    • Publication Date:
      Date Created: 20221112 Date Completed: 20221115 Latest Revision: 20221115
    • Publication Date:
      20231215
    • Accession Number:
      10.1007/978-1-0716-2744-0_1
    • Accession Number:
      36370338