Modular robotic platform for precision neurosurgery with a bio-inspired needle: System overview and first in-vivo deployment.

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  • Additional Information
    • Source:
      Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
    • Publication Information:
      Original Publication: San Francisco, CA : Public Library of Science
    • Subject Terms:
      Neurosurgery*/methods ; Robotic Surgical Procedures*/methods ; Robotics*/methods; Animals ; Sheep ; Humans ; Neurosurgical Procedures ; Minimally Invasive Surgical Procedures/methods
    • Abstract:
      Over the past 10 years, minimally invasive surgery (MIS) has shown significant benefits compared to conventional surgical techniques, with reduced trauma, shorter hospital stays, and shorter patient recovery times. In neurosurgical MIS procedures, inserting a straight tool (e.g. catheter) is common practice in applications ranging from biopsy and laser ablation, to drug delivery and fluid evacuation. How to handle tissue deformation, target migration and access to deep-seated anatomical structures remain an open challenge, affecting both the preoperative planning phase and eventual surgical intervention. Here, we present the first neurosurgical platform in the literature, able to deliver an implantable steerable needle for a range of diagnostic and therapeutic applications, with a short-term focus on localised drug delivery. This work presents the system's architecture and first in vivo deployment with an optimised surgical workflow designed for pre-clinical trials with the ovine model, which demonstrate appropriate function and safe implantation.
      Competing Interests: The authors have declared that no competing interests exist.
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    • Publication Date:
      Date Created: 20221019 Date Completed: 20221021 Latest Revision: 20221022
    • Publication Date:
      20221213
    • Accession Number:
      PMC9581417
    • Accession Number:
      10.1371/journal.pone.0275686
    • Accession Number:
      36260553