The effects of the COVID-19 pandemic on community respiratory virus activity.

Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101190261 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1740-1534 (Electronic) Linking ISSN: 17401526 NLM ISO Abbreviation: Nat Rev Microbiol Subsets: MEDLINE

Original Publication: London, UK : Nature Pub. Group, c2003-

COVID-19*/epidemiology ; COVID-19*/prevention & control ; Viruses*; Humans ; SARS-CoV-2 ; COVID-19 Vaccines ; Pandemics

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused substantial global morbidity and deaths, leading governments to turn to non-pharmaceutical interventions to slow down the spread of infection and lessen the burden on health care systems. These policies have evolved over the course of the COVID-19 pandemic, including after the availability of COVID-19 vaccines, with regional and country-level differences in their ongoing use. The COVID-19 pandemic has been associated with changes in respiratory virus infections worldwide, which have differed between virus types. Reductions in respiratory virus infections, including by influenza virus and respiratory syncytial virus, were most notable at the onset of the COVID-19 pandemic and continued in varying degrees through subsequent waves of SARS-CoV-2 infections. The decreases in community infection burden have resulted in reduced hospitalizations and deaths associated with non-SARS-CoV-2 respiratory infections. Respiratory virus evolution relies on the maintaining of a diverse genetic pool, but evidence of genetic bottlenecking brought on by case reduction during the COVID-19 pandemic has resulted in reduced genetic diversity of some respiratory viruses, including influenza virus. By describing the differences in these changes between viral species across different geographies over the course of the COVID-19 pandemic, we may better understand the complex factors involved in community co-circulation of respiratory viruses.
(© 2022. Springer Nature Limited.)

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T32 AI007044 United States AI NIAID NIH HHS

0 (COVID-19 Vaccines)

Date Created: 20221017 Date Completed: 20230217 Latest Revision: 20230417

20240628

PMC9574826

10.1038/s41579-022-00807-9

36253478