Metastasis of the Mucionous adenocarcinoma of breast to the mandibular gingiva: Rare case report.

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
Read More Add to Saved list
  • Additional Information
    • Source:
      Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 2985248R Publication Model: Print Cited Medium: Internet ISSN: 1536-5964 (Electronic) Linking ISSN: 00257974 NLM ISO Abbreviation: Medicine (Baltimore) Subsets: MEDLINE
    • Publication Information:
      Original Publication: Hagerstown, Md : Lippincott Williams & Wilkins
    • Subject Terms:
      Adenocarcinoma*/pathology ; Breast Neoplasms*/diagnosis ; Breast Neoplasms*/pathology ; Carcinoma, Lobular*; Female ; Gingiva/pathology ; Humans ; Melanoma ; Mucins ; Skin Neoplasms ; Melanoma, Cutaneous Malignant
    • Abstract:
      Introduction: Mucinous adenocarcinoma (MAC) is a rare type of cancer in which more than 50% of the tumor is composed of extracellular mucin and malignant epithelial cells. MACs account for only 1.8% of all breast cancer cases. Most breast cancers present as localized diseases and are well-differentiated. Breast MAC has a better 5- and 10-year survival rate than ductal and lobular carcinomas. Distant metastasis in breast MAC is rare, especially in the oral cavity. Only 1% of all oral malignancies present with metastases to the oral cavity. The bony structures are more involved than the soft tissues. Involvement of the oral soft tissue is rare, accounting for less than 0.1% of oral metastases.
      Case Description: This report describes a rare case of mucinous breast adenocarcinoma with metastasis to the mandibular molar region. Diagnosis was established based on anamnesis, clinical presentation, tumor biopsy, computed tomography, mammography, and core biopsy of the breast tumor. The patient was sent to the oncology committee for breast disease where chemotherapy was indicated.
      Discussion: The clinical presentation of oral metastasis is not pathognomonic, and pyogenic granuloma, periodontal abscesses, sarcomas, and squamous carcinoma must be considered in the differential diagnosis. This is a rare case of oral metastasis of breast MAC, which was indicated for detection of the primary tumor.
      Competing Interests: The authors have no funding and conflicts of interest to disclose.
      (Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.)
    • References:
      Med Oral Patol Oral Cir Bucal. 2021 Sep 1;26(5):e619-e625. (PMID: 34023842)
      Cancers (Basel). 2020 Oct 30;12(11):. (PMID: 33143115)
      Oral Maxillofac Surg. 2018 Jun;22(2):119-128. (PMID: 29344820)
      Breast. 2020 Feb;49:87-92. (PMID: 31783314)
      J Pathol Transl Med. 2020 Jan;54(1):95-102. (PMID: 31718120)
      Breast Cancer Res Treat. 2008 Oct;111(3):541-7. (PMID: 18026874)
      Sci Rep. 2021 Mar 11;11(1):5770. (PMID: 33707745)
      J Med Case Rep. 2011 Jul 01;5:265. (PMID: 21722359)
      Int J Gen Med. 2021 Dec 18;14:9991-10001. (PMID: 34984023)
      J Stomatol Oral Maxillofac Surg. 2018 Jun;119(3):229-231. (PMID: 29475082)
      J Breast Cancer. 2011 Dec;14(4):308-13. (PMID: 22323918)
      Oral Dis. 2022 Jan;28(1):23-32. (PMID: 32790941)
      Medicine (Baltimore). 2018 Apr;97(15):e0296. (PMID: 29642152)
    • Accession Number:
      0 (Mucins)
    • Publication Date:
      Date Created: 20221005 Date Completed: 20221007 Latest Revision: 20231213
    • Publication Date:
      20231215
    • Accession Number:
      PMC9509197
    • Accession Number:
      10.1097/MD.0000000000030732
    • Accession Number:
      36197223