Item request has been placed!
×
Item request cannot be made.
×
Processing Request
Whole-genome sequence and assembly of the Javan gibbon (Hylobates moloch).
Item request has been placed!
×
Item request cannot be made.
×
Processing Request
- Additional Information
- Source:
Publisher: Oxford University Press For The American Genetic Association Country of Publication: United States NLM ID: 0375373 Publication Model: Print Cited Medium: Internet ISSN: 1465-7333 (Electronic) Linking ISSN: 00221503 NLM ISO Abbreviation: J Hered Subsets: MEDLINE
- Publication Information:
Publication: New York, NY : Oxford University Press For The American Genetic Association
Original Publication: Baltimore [etc.] American Genetic Assn.
- Subject Terms:
- Abstract:
The Javan gibbon, Hylobates moloch, is an endangered gibbon species restricted to the forest remnants of western and central Java, Indonesia, and one of the rarest of the Hylobatidae family. Hylobatids consist of 4 genera (Holoock, Hylobates, Symphalangus, and Nomascus) that are characterized by different numbers of chromosomes, ranging from 38 to 52. The underlying cause of this karyotype plasticity is not entirely understood, at least in part, due to the limited availability of genomic data. Here we present the first scaffold-level assembly for H. moloch using a combination of whole-genome Illumina short reads, 10X Chromium linked reads, PacBio, and Oxford Nanopore long reads and proximity-ligation data. This Hylobates genome represents a valuable new resource for comparative genomics studies in primates.
(© The American Genetic Association. 2022.)
- Grant Information:
P51 OD011092 United States OD NIH HHS; R01 GM130691 United States GM NIGMS NIH HHS; R01GM130691 United States GM NIGMS NIH HHS; 5U24HG00908103 United States HG NHGRI NIH HHS; S10 OD018174 United States OD NIH HHS; R01 HG010333 United States HG NHGRI NIH HHS
- Contributed Indexing:
Keywords: Hi-C; genome assembly; gibbon; long reads; proximity ligation
- Publication Date:
Date Created: 20220923 Date Completed: 20230321 Latest Revision: 20240504
- Publication Date:
20240504
- Accession Number:
PMC10019027
- Accession Number:
10.1093/jhered/esac043
- Accession Number:
36146896
No Comments.