Curcumin Combats against Organophosphate Pesticides Toxicity: A Review of the Current Evidence and Molecular Pathways.

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  • Additional Information
    • Source:
      Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 9440157 Publication Model: Print Cited Medium: Internet ISSN: 1875-533X (Electronic) Linking ISSN: 09298673 NLM ISO Abbreviation: Curr Med Chem Subsets: MEDLINE
    • Publication Information:
      Publication: Saif Zone, Sharjah, U.A.E. : Bentham Science Publishers
      Original Publication: Schiphol, The Netherlands : Bentham Science Publishers,
    • Subject Terms:
      Curcumin*/pharmacology ; Pesticides*/toxicity; Animals ; Humans ; Medicine, Traditional ; Anti-Inflammatory Agents/pharmacology ; Organophosphates
    • Abstract:
      Organophosphate compounds are regarded as a class of pesticides that are used in farming. Their extensive use, especially in developing countries, is a serious public health problem. Numerous studies have shown the effects of these toxins on various parts of the human and other vertebrates' bodies, including the cardiovascular, hepatobiliary, renal, and reproductive systems. Curcumin is a polyphenol compound obtained from the rhizome of the Curcuma longa. Curcumin has been known as a dietary spice, food additive, and traditional medicine since many years ago. In recent decades, the medicinal characteristics, clinical aspects, and biological activity of curcumin have been extensively examined. The most examined positive characteristics of curcumin are its anti- inflammatory and anti-oxidant qualities. This review will deal with the pharmacological properties of curcumin as well as an update of currently available studies in terms of curcumin's uses and function against organophosphate pesticides-induced toxicity on different human organs.
      (Copyright© Bentham Science Publishers; For any queries, please email at [email protected].)
    • Contributed Indexing:
      Keywords: Curcumin; organophosphate; pesticides; toxicity; toxins
    • Accession Number:
      IT942ZTH98 (Curcumin)
      0 (Anti-Inflammatory Agents)
      0 (Pesticides)
      0 (Organophosphates)
    • Publication Date:
      Date Created: 20220818 Date Completed: 20230519 Latest Revision: 20230519
    • Publication Date:
      20231215
    • Accession Number:
      10.2174/0929867329666220817125800
    • Accession Number:
      35980068