Takotsubo cardiomyopathy in the setting of thyroid storm.

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  • Additional Information
    • Source:
      Publisher: BMJ Pub. Group Country of Publication: England NLM ID: 101526291 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-790X (Electronic) Linking ISSN: 1757790X NLM ISO Abbreviation: BMJ Case Rep Subsets: MEDLINE
    • Publication Information:
      Original Publication: London : BMJ Pub. Group
    • Subject Terms:
      Acute Coronary Syndrome*/complications ; Coronary Artery Disease*/complications ; Takotsubo Cardiomyopathy*/complications ; Takotsubo Cardiomyopathy*/diagnosis ; Thyroid Crisis*/complications ; Thyroid Crisis*/diagnosis; Coronary Angiography/adverse effects ; Female ; Humans
    • Abstract:
      A woman in her 50s with a background of chronic obstructive pulmonary disease secondary to smoking presented with intermittent chest tightness, dyspnoea and vomiting for 4 days. A presumed diagnosis of acute coronary syndrome (ACS) was made based on dynamic ischaemic ECG changes and elevation in high-sensitivity cardiac troponin T levels. She underwent emergent coronary angiography which demonstrated mild coronary artery disease with left ventriculography suggestive of mid-wall variant Takotsubo cardiomyopathy. Thyroid function tests performed to investigate sinus tachycardia were consistent with hyperthyroidism, and her thyroid-stimulating hormone receptor antibody was elevated. A diagnosis of thyroid storm was made in the setting of a newly diagnosed Graves' disease and the patient was subsequently commenced on guideline-based therapy. This case demonstrates that Takotsubo cardiomyopathy, a mimic of ACS, is a possible complication of thyroid storm and therefore hyperthyroidism should be considered in the list of differentials in patients presenting with Takotsubo cardiomyopathy.
      Competing Interests: Competing interests: None declared.
      (© BMJ Publishing Group Limited 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
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    • Contributed Indexing:
      Keywords: Cardiovascular medicine; Clinical diagnostic tests; Heart failure; Thyroid disease; Thyrotoxicosis
    • Publication Date:
      Date Created: 20220513 Date Completed: 20220517 Latest Revision: 20220716
    • Publication Date:
      20221213
    • Accession Number:
      PMC9109024
    • Accession Number:
      10.1136/bcr-2021-248353
    • Accession Number:
      35550326