Ophthalmic features and management of 86 patients with cryptophthalmos-A refined classification to assist in surgical planning.

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  • Additional Information
    • Source:
      Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101264239 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-0539 (Electronic) Linking ISSN: 17486815 NLM ISO Abbreviation: J Plast Reconstr Aesthet Surg Subsets: MEDLINE
    • Publication Information:
      Original Publication: Amsterdam, The Netherlands : Elsevier, c2006-
    • Subject Terms:
      Anophthalmos*/surgery ; Cysts* ; Microphthalmos*/complications ; Microphthalmos*/surgery; Eyelids/abnormalities ; Eyelids/surgery ; Female ; Humans ; Retrospective Studies
    • Abstract:
      Background/aims: This study aimed to describe a cohort of patients with cryptophthalmos (CO), characterize associated oculofacial abnormalities, and expand the classification to summarize surgical strategies for managing CO.
      Methods: A retrospective, interventional case series was conducted on 86 patients (124 eyes) with CO. The study proposed further classifying complete and incomplete CO into cyst, microphthalmia, anophthalmia, and normal eyeball based on globe structures and then modifying surgery accordingly. The demography, ophthalmic features, systemic anomalies, operation methods, and treatment outcomes were reviewed.
      Results: CO was complete in seven eyes (5.6%) and incomplete in eight eyes (6.5%). A total of 109 eyes (87.9%) of abortive CO were encountered. Among 15 eyes (13 patients) of complete and incomplete types, 9 (60.0%) eyeballs were identified as cysts, 3 (20.0%) as microphthalmia, 1 (6.7%) as anophthalmia, and 2 (13.3%) as normal eyeballs. Cyst reduction was performed in eight eyes and one patient underwent enucleation with hydroxyapatite implantation. The socket was fit with an ocular prosthesis or a conformer after fornix and eyelid reconstruction. Microphthalmia was enucleated, and hydroxyapatites were implanted; patients were fit with ocular prosthesis or conformer after fornix and eyelid reconstruction. A complete CO with normal eyeball was reported with the eyesight of hand movement after ocular surface reconstruction. The upper eyelid contour and adequate fornix were maintained after coloboma repair and fornix reconstruction in all patients with abortive CO.
      Conclusion: This study demonstrates the clinical manifestations of different types of CO and expands the manifestation spectrum, proposing a refined classification of CO and modifying surgical strategies accordingly.
      Competing Interests: Declaration of Competing Interest All the authors have indicated that they have no potential conflicts of interest to disclose.
      (Copyright © 2022 Elsevier Ltd. All rights reserved.)
    • Comments:
      Comment in: J Plast Reconstr Aesthet Surg. 2022 Jul;75(7):2266-2267. (PMID: 35296380)
    • Contributed Indexing:
      Keywords: Cryptophthalmos; Eyeball structures; Ophthalmic features; Surgical strategies
    • Publication Date:
      Date Created: 20220320 Date Completed: 20220713 Latest Revision: 20220807
    • Publication Date:
      20231215
    • Accession Number:
      10.1016/j.bjps.2022.02.007
    • Accession Number:
      35305918