Unraveling the potential of non-conventional yeasts in biotechnology.

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  • Additional Information
    • Source:
      Publisher: Oxford University Press Country of Publication: England NLM ID: 101085384 Publication Model: Print Cited Medium: Internet ISSN: 1567-1364 (Electronic) Linking ISSN: 15671356 NLM ISO Abbreviation: FEMS Yeast Res Subsets: MEDLINE
    • Publication Information:
      Publication: 2015- : Oxford Oxford University Press
      Original Publication: Amsterdam ; New York : Published by Elsevier Science B.V. on behalf of Federation of European Microbiological Societies, [2001-
    • Subject Terms:
      Biotechnology* ; Metabolic Engineering*; Biofuels ; Fermentation ; Saccharomyces cerevisiae/genetics ; Yeasts/genetics
    • Abstract:
      Cost-effective microbial conversion processes of renewable feedstock into biofuels and biochemicals are of utmost importance for the establishment of a robust bioeconomy. Conventional baker's yeast Saccharomyces cerevisiae, widely employed in biotechnology for decades, lacks many of the desired traits for such bioprocesses like utilization of complex carbon sources or low tolerance towards challenging conditions. Many non-conventional yeasts (NCY) present these capabilities, and they are therefore forecasted to play key roles in future biotechnological production processes. For successful implementation of NCY in biotechnology, several challenges including generation of alternative carbon sources, development of tailored NCY and optimization of the fermentation conditions are crucial for maximizing bioproduct yields and titers. Addressing these challenges requires a multidisciplinary approach that is facilitated through the 'YEAST4BIO' COST action. YEAST4BIO fosters integrative investigations aimed at filling knowledge gaps and excelling research and innovation, which can improve biotechnological conversion processes from renewable resources to mitigate climate change and boost transition towards a circular bioeconomy. In this perspective, the main challenges and research efforts within YEAST4BIO are discussed, highlighting the importance of collaboration and knowledge exchange for progression in this research field.
      (© The Author(s) 2022. Published by Oxford University Press on behalf of FEMS.)
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    • Grant Information:
      Chalmers University of Technology; European Cooperation in Science and Technology
    • Contributed Indexing:
      Keywords: biochemicals; biofuels; lignocellulosic sugars; non-conventional yeasts; volatile fatty acids
    • Accession Number:
      0 (Biofuels)
    • Publication Date:
      Date Created: 20220118 Date Completed: 20220131 Latest Revision: 20220131
    • Publication Date:
      20221213
    • Accession Number:
      PMC8793870
    • Accession Number:
      10.1093/femsyr/foab071
    • Accession Number:
      35040953