Acute kidney injury due to ammonium acid urate stones in a patient with adenovirus gastroenteritis: a case report.

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  • Additional Information
    • Source:
      Publisher: BioMed Central Country of Publication: England NLM ID: 100968571 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2490 (Electronic) Linking ISSN: 14712490 NLM ISO Abbreviation: BMC Urol Subsets: MEDLINE
    • Publication Information:
      Original Publication: London : BioMed Central, [2001-
    • Subject Terms:
      Uric Acid*/analysis; Acute Kidney Injury/*etiology ; Adenoviridae Infections/*complications ; Gastroenteritis/*complications ; Urinary Calculi/*complications; Gastroenteritis/virology ; Humans ; Infant ; Male ; Urinary Calculi/chemistry
    • Abstract:
      Background: Adenovirus gastroenteritis is a common cause of diarrhea and vomiting in infants, resulting in prerenal acute kidney injury (AKI). However, postrenal AKI due to urinary stones associated with adenovirus gastroenteritis is extremely rare. Here, we describe postrenal AKI due to obstructive ammonium acid urate stones associated with adenovirus gastroenteritis.
      Case Presentation: A previously healthy 6-month-old boy had an 11-day history of severe diarrhea and a 5-day history of vomiting. His stool was positive for adenovirus antigens. We initiated fluid replacement therapy. On the second hospital day, he suddenly developed anuria. Abdominal computed tomography revealed bilateral hydronephrosis, left ureteral stones, and right bladder ureteral junction stones. Laboratory data showed that the creatinine level increased to 1.00 mg/dL. We diagnosed postrenal AKI due to obstructive bilateral urinary stones. Urination with stable urine volume resumed spontaneously after hydration. A few stones were found in the urine, which consisted of ammonium acid urate (> 98%). The serum creatinine level improved to 0.25 mg/dL. He was discharged nine days after admission.
      Conclusions: We suggest that adenovirus gastroenteritis be considered in pediatric patients with postrenal AKI due to urinary stones.
      (© 2022. The Author(s).)
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    • Contributed Indexing:
      Keywords: Acute kidney injury; Adenovirus gastroenteritis; Ammonium acid urate stone; Case report; Infant
    • Accession Number:
      268B43MJ25 (Uric Acid)
    • Publication Date:
      Date Created: 20220116 Date Completed: 20220303 Latest Revision: 20220303
    • Publication Date:
      20240829
    • Accession Number:
      PMC8760781
    • Accession Number:
      10.1186/s12894-022-00954-4
    • Accession Number:
      35033051