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Comprehensive Management of Cardiovascular Risk Factors for Adults With Type 2 Diabetes: A Scientific Statement From the American Heart Association.
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- Author(s): Joseph JJ; Deedwania P; Acharya T; Aguilar D; Bhatt DL; Chyun DA; Di Palo KE; Golden SH; Sperling LS
- Source:
Circulation [Circulation] 2022 Mar; Vol. 145 (9), pp. e722-e759. Date of Electronic Publication: 2022 Jan 10.- Publication Type:
Journal Article; Review- Language:
English - Source:
- Additional Information
- Corporate Authors:
- Source: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0147763 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4539 (Electronic) Linking ISSN: 00097322 NLM ISO Abbreviation: Circulation Subsets: MEDLINE
- Publication Information: Publication: Hagerstown, MD : Lippincott Williams & Wilkins
Original Publication: [Dallas, Tex., etc., American Heart Association, etc.] - Subject Terms: Cardiovascular Diseases*/epidemiology ; Cardiovascular Diseases*/etiology ; Cardiovascular Diseases*/prevention & control ; Diabetes Complications*/epidemiology ; Diabetes Complications*/prevention & control ; Diabetes Mellitus, Type 2*/drug therapy ; Diabetes Mellitus, Type 2*/epidemiology; Adult ; American Heart Association ; Heart Disease Risk Factors ; Humans ; United States/epidemiology
- Abstract: Cardiovascular disease remains the leading cause of death in patients with diabetes. Cardiovascular disease in diabetes is multifactorial, and control of the cardiovascular risk factors leads to substantial reductions in cardiovascular events. The 2015 American Heart Association and American Diabetes Association scientific statement, "Update on Prevention of Cardiovascular Disease in Adults With Type 2 Diabetes Mellitus in Light of Recent Evidence," highlighted the importance of modifying various risk factors responsible for cardiovascular disease in diabetes. At the time, there was limited evidence to suggest that glucose-lowering medications reduce the risk of cardiovascular events. At present, several large randomized controlled trials with newer antihyperglycemic agents have been completed, demonstrating cardiovascular safety and reduction in cardiovascular outcomes, including cardiovascular death, myocardial infarction, stroke, and heart failure. This AHA scientific statement update focuses on (1) the evidence and clinical utility of newer antihyperglycemic agents in improving glycemic control and reducing cardiovascular events in diabetes; (2) the impact of blood pressure control on cardiovascular events in diabetes; and (3) the role of newer lipid-lowering therapies in comprehensive cardiovascular risk management in adults with diabetes. This scientific statement addresses the continued importance of lifestyle interventions, pharmacological therapy, and surgical interventions to curb the epidemic of obesity and metabolic syndrome, important precursors of prediabetes, diabetes, and comorbid cardiovascular disease. Last, this scientific statement explores the critical importance of the social determinants of health and health equity in the continuum of care in diabetes and cardiovascular disease.
- Contributed Indexing: Keywords: AHA Scientific Statements; antihypertensive agents; cardiovascular diseases; diabetes complications; hypoglycemic agents; life style; social determinants of health
- Publication Date: Date Created: 20220110 Date Completed: 20220310 Latest Revision: 20220310
- Publication Date: 20221213
- Accession Number: 10.1161/CIR.0000000000001040
- Accession Number: 35000404
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