Direct observation in a large-scale randomized trial of parent training in children with autism spectrum disorder and disruptive behavior.

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  • Additional Information
    • Source:
      Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101300021 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1750-9467 (Print) NLM ISO Abbreviation: Res Autism Spectr Disord Subsets: PubMed not MEDLINE
    • Publication Information:
      Original Publication: Amsterdam : Elsevier
    • Abstract:
      A direct observation strategy (Standardized Observation Analogue Procedure, SOAP) was used in a large-scale randomized trial of parent training versus parent education in young children with autism spectrum disorder (ASD) and disruptive behavior. The 16-minute SOAP, modified from an earlier version of this same measure, included parentchild interaction to assess child behavior in a clinical laboratory setting. Despite study entry criteria for all child participants requiring moderate levels of disruptive behavior in this project, 126 of 168 children with complete SOAP data at baseline showed no disruptive behavior on this measure. Although the primary purpose of the study was to determine whether the SOAP could detect differences between the two conditions (i.e.,parent training (PT) and parent education (PE)), baseline observation data was not consistent with parent ratings at baseline or subsequent follow up visits, leaving little room to demonstrate improvement with this observation measure. This and the challenging, time-consuming and resource intensive effort involved in using such a measure in a large randomized scale trial, raises fundamental questions about the validity of the SOAP as an outcome measure in such a study. Further consideration related to the feasibility and practicality of using direct observation as a primary measure in larger scale efforts overall are also discussed.
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    • Grant Information:
      R01 MH080965 United States MH NIMH NIH HHS; UL1 TR001863 United States TR NCATS NIH HHS; R01 MH081105 United States MH NIMH NIH HHS; R01 MH080906 United States MH NIMH NIH HHS; R01 MH081221 United States MH NIMH NIH HHS; R01 MH081148 United States MH NIMH NIH HHS
    • Contributed Indexing:
      Keywords: Assessment; Autism spectrum disorder (ASD); Behavioral; Randomized Control Trial (RCT); behavioral intervention; direct observation; parent and caregiver training
    • Publication Date:
      Date Created: 20211224 Latest Revision: 20240404
    • Publication Date:
      20240404
    • Accession Number:
      PMC8691726
    • Accession Number:
      10.1016/j.rasd.2021.101879
    • Accession Number:
      34950225