Type 2 diabetes after a pregnancy with gestational diabetes among first nations women in Australia: The PANDORA study.

Publisher: Elsevier Scientific Publishers Country of Publication: Ireland NLM ID: 8508335 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8227 (Electronic) Linking ISSN: 01688227 NLM ISO Abbreviation: Diabetes Res Clin Pract Subsets: MEDLINE

Publication: 1993- : Limerick : Elsevier Scientific Publishers
Original Publication: Amsterdam : Elsevier Science Publishers B.V., c1985-

Diabetes Mellitus, Type 2*/epidemiology ; Diabetes, Gestational*/epidemiology ; Prediabetic State* ; Pregnancy in Diabetics*; Aged ; Female ; Humans ; Postpartum Period ; Pregnancy ; Prospective Studies ; Risk Factors

Aims: To determine among First Nations and Europid pregnant women the cumulative incidence and predictors of postpartum type 2 diabetes and prediabetes and describe postpartum cardiovascular disease (CVD) risk profiles.
Methods: PANDORA is a prospective longitudinal cohort of women recruited in pregnancy. Ethnic-specific rates of postpartum type 2 diabetes and prediabetes were reported for women with diabetes in pregnancy (DIP), gestational diabetes (GDM) or normoglycaemia in pregnancy over a short follow-up of 2.5 years (n = 325). Pregnancy characteristics and CVD risk profiles according to glycaemic status, and factors associated with postpartum diabetes/prediabetes were examined in First Nations women.
Results: The cumulative incidence of postpartum type 2 diabetes among women with DIP or GDM were higher for First Nations women (48%, 13/27, women with DIP, 13%, 11/82, GDM), compared to Europid women (nil DIP or GDM p < 0.001). Characteristics associated with type 2 diabetes/prediabetes among First Nations women with GDM/DIP included, older age, multiparity, family history of diabetes, higher glucose values, insulin use and body mass index (BMI).
Conclusions: First Nations women experience a high incidence of postpartum type 2 diabetes after GDM/DIP, highlighting the need for culturally responsive policies at an individual and systems level, to prevent diabetes and its complications.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2021 The Author(s). Published by Elsevier B.V. All rights reserved.)

Erratum in: Diabetes Res Clin Pract. 2024 May 7;:111687. (PMID: 38719761)

Keywords: Diabetes in pregnancy; Gestational diabetes; Indigenous health

Date Created: 20211015 Date Completed: 20211123 Latest Revision: 20240508

20240509

10.1016/j.diabres.2021.109092

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