Menu
×
West Ashley Library
Closed
Phone: (843) 766-6635
Folly Beach Library
Closed
Phone: (843) 588-2001
Edgar Allan Poe/Sullivan's Island Library
Closed for renovations
Phone: (843) 883-3914
Wando Mount Pleasant Library
Closed
Phone: (843) 805-6888
Village Library
Closed
Phone: (843) 884-9741
St. Paul's/Hollywood Library
Closed
Phone: (843) 889-3300
Otranto Road Library
Closed
Phone: (843) 572-4094
Mt. Pleasant Library
Closed
Phone: (843) 849-6161
McClellanville Library
Closed
Phone: (843) 887-3699
Keith Summey North Charleston Library
Closed
Phone: (843) 744-2489
John's Island Library
Closed
Phone: (843) 559-1945
Hurd/St. Andrews Library
Closed
Phone: (843) 766-2546
Miss Jane's Building (Edisto Library Temporary Location)
Closed
Phone: (843) 869-2355
Dorchester Road Library
Closed
Phone: (843) 552-6466
John L. Dart Library
Closed
Phone: (843) 722-7550
Baxter-Patrick James Island
Closed
Phone: (843) 795-6679
Main Library
2 p.m. – 5 p.m.
Phone: (843) 805-6930
Bees Ferry West Ashley Library
Closed
Phone: (843) 805-6892
Mobile Library
Closed
Phone: (843) 805-6909
Today's Hours
West Ashley Library
Closed
Phone: (843) 766-6635
Folly Beach Library
Closed
Phone: (843) 588-2001
Edgar Allan Poe/Sullivan's Island Library
Closed for renovations
Phone: (843) 883-3914
Wando Mount Pleasant Library
Closed
Phone: (843) 805-6888
Village Library
Closed
Phone: (843) 884-9741
St. Paul's/Hollywood Library
Closed
Phone: (843) 889-3300
Otranto Road Library
Closed
Phone: (843) 572-4094
Mt. Pleasant Library
Closed
Phone: (843) 849-6161
McClellanville Library
Closed
Phone: (843) 887-3699
Keith Summey North Charleston Library
Closed
Phone: (843) 744-2489
John's Island Library
Closed
Phone: (843) 559-1945
Hurd/St. Andrews Library
Closed
Phone: (843) 766-2546
Miss Jane's Building (Edisto Library Temporary Location)
Closed
Phone: (843) 869-2355
Dorchester Road Library
Closed
Phone: (843) 552-6466
John L. Dart Library
Closed
Phone: (843) 722-7550
Baxter-Patrick James Island
Closed
Phone: (843) 795-6679
Main Library
2 p.m. – 5 p.m.
Phone: (843) 805-6930
Bees Ferry West Ashley Library
Closed
Phone: (843) 805-6892
Mobile Library
Closed
Phone: (843) 805-6909
Patron Login
menu
Item request has been placed!
×
Item request cannot be made.
×
![loading](/sites/all/modules/hf_eds/images/loading.gif)
Rapid diagnosis of COVID-19 using FT-IR ATR spectroscopy and machine learning.
Item request has been placed!
×
Item request cannot be made.
×
![loading](/sites/all/modules/hf_eds/images/loading.gif)
- Author(s): Nogueira MS;Nogueira MS; Leal LB; Leal LB; Marcarini WD; Marcarini WD; Marcarini WD; Pimentel RL; Pimentel RL; Muller M; Muller M; Vassallo PF; Vassallo PF; Campos LCG; Campos LCG; Dos Santos L; Dos Santos L; Luiz WB; Luiz WB; Mill JG; Mill JG; Barauna VG; Barauna VG; de Carvalho LFDCES; de Carvalho LFDCES; de Carvalho LFDCES
- Source:
Scientific reports [Sci Rep] 2021 Oct 11; Vol. 11 (1), pp. 15409. Date of Electronic Publication: 2021 Oct 11.- Publication Type:
Journal Article; Research Support, Non-U.S. Gov't- Language:
English - Source:
- Additional Information
- Source: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
- Publication Information: Original Publication: London : Nature Publishing Group, copyright 2011-
- Subject Terms: COVID-19/*diagnosis ; COVID-19 Testing/*methods ; SARS-CoV-2/*isolation & purification ; Spectroscopy, Fourier Transform Infrared/*methods; Adult ; Aged ; Brazil/epidemiology ; COVID-19/epidemiology ; Early Diagnosis ; Female ; Humans ; Least-Squares Analysis ; Machine Learning ; Male ; Middle Aged ; Time Factors
- Abstract: Early diagnosis of COVID-19 in suspected patients is essential for contagion control and damage reduction strategies. We investigated the applicability of attenuated total reflection (ATR) Fourier transform infrared (FTIR) spectroscopy associated with machine learning in oropharyngeal swab suspension fluid to predict COVID-19 positive samples. The study included samples of 243 patients from two Brazilian States. Samples were transported by using different viral transport mediums (liquid 1 or 2). Clinical COVID-19 diagnosis was performed by the RT-PCR. We built a classification model based on partial least squares (PLS) associated with cosine k-nearest neighbours (KNN). Our analysis led to 84% and 87% sensitivity, 66% and 64% specificity, and 76.9% and 78.4% accuracy for samples of liquids 1 and 2, respectively. Based on this proof-of-concept study, we believe this method could offer a simple, label-free, cost-effective solution for high-throughput screening of suspect patients for COVID-19 in health care centres and emergency departments.
(© 2021. The Author(s).) - Comments: Erratum in: Sci Rep. 2021 Nov 24;11(1):23153. (PMID: 34819597)
- References: J Biophotonics. 2018 May;11(5):e201700252. (PMID: 29243883)
Clin Oral Investig. 2019 Jul;23(7):3021-3031. (PMID: 30402700)
N Engl J Med. 2020 Feb 20;382(8):727-733. (PMID: 31978945)
J Med Virol. 2020 Jul;92(7):903-908. (PMID: 32219885)
Front Immunol. 2020 Oct 14;11:585354. (PMID: 33163000)
J Biophotonics. 2018 Jul;11(7):e201700372. (PMID: 29512302)
Eur Radiol. 2020 Aug;30(8):4381-4389. (PMID: 32193638)
J Clin Microbiol. 2020 Apr 23;58(5):. (PMID: 32132196)
Biomed Opt Express. 2018 Jan 16;9(2):649. (PMID: 29553144)
Am J Infect Control. 2021 Jan;49(1):21-29. (PMID: 32659413)
J Photochem Photobiol B. 2019 Sep;198:111580. (PMID: 31394353)
Analyst. 2018 Dec 3;143(24):6037-6048. (PMID: 30403209)
Photodiagnosis Photodyn Ther. 2020 Sep;31:101892. (PMID: 32585401)
Photodiagnosis Photodyn Ther. 2020 Sep;31:101890. (PMID: 32585400)
ACS Nano. 2020 Apr 28;14(4):3822-3835. (PMID: 32223179)
Exp Mol Pathol. 2015 Jun;98(3):502-9. (PMID: 25805102)
West J Emerg Med. 2020 Apr 13;21(3):470-472. (PMID: 32302278)
Photodiagnosis Photodyn Ther. 2020 Sep;31:101836. (PMID: 32473399)
Exp Mol Pathol. 2017 Dec;103(3):255-262. (PMID: 29126766)
Int J Oral Sci. 2020 Mar 3;12(1):9. (PMID: 32127517)
Nat Commun. 2019 Oct 8;10(1):4501. (PMID: 31594931)
Biomed Opt Express. 2017 Oct 24;8(11):5218-5227. (PMID: 29188115)
Photodiagnosis Photodyn Ther. 2020 Sep;31:101823. (PMID: 32445960)
Eur Rev Med Pharmacol Sci. 2020 Apr;24(7):4016-4026. (PMID: 32329877)
J Biophotonics. 2018 Mar;11(3):. (PMID: 28949439)
Photodiagnosis Photodyn Ther. 2020 Jun;30:101765. (PMID: 32304912)
Photodiagnosis Photodyn Ther. 2018 Dec;24:237-244. (PMID: 30282049)
Analyst. 2018 Apr 16;143(8):1735-1757. (PMID: 29504623)
J Biophotonics. 2020 May;13(5):e201960094. (PMID: 31999078)
JAMA. 2020 Jun 9;323(22):2249-2251. (PMID: 32374370)
Photodiagnosis Photodyn Ther. 2016 Dec;16:27-34. (PMID: 27491855)
Emerg Microbes Infect. 2020 Dec;9(1):747-756. (PMID: 32196430) - Publication Date: Date Created: 20211012 Date Completed: 20211020 Latest Revision: 20211126
- Publication Date: 20240628
- Accession Number: PMC8505540
- Accession Number: 10.1038/s41598-021-93511-2
- Accession Number: 34635702
- Source:
Contact CCPL
Copyright 2022 Charleston County Public Library Powered By EBSCO Stacks 3.3.0 [350.3] | Staff Login
No Comments.