The effects of additional electrical stimulation combined with repetitive transcranial magnetic stimulation and motor imagery on upper extremity motor recovery in the subacute period after stroke: A preliminary study.

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  • Additional Information
    • Source:
      Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 2985248R Publication Model: Print Cited Medium: Internet ISSN: 1536-5964 (Electronic) Linking ISSN: 00257974 NLM ISO Abbreviation: Medicine (Baltimore) Subsets: MEDLINE
    • Publication Information:
      Original Publication: Hagerstown, Md : Lippincott Williams & Wilkins
    • Subject Terms:
      Electric Stimulation* ; Stroke Rehabilitation* ; Transcranial Magnetic Stimulation*; Hemiplegia/*therapy ; Upper Extremity/*physiology; Aged ; Female ; Hemiplegia/etiology ; Humans ; Male ; Middle Aged ; Prospective Studies ; Recovery of Function ; Stroke/complications ; Subacute Care
    • Abstract:
      Background: To evaluate the therapeutic effects of additional electrical stimulation (ES) combined with low frequency (LF)-repetitive transcranial magnetic stimulation (rTMS) and motor imagery (MI) training on upper extremity (UE) motor function following stroke.
      Methods: The participants with subacute stroke in the experimental group (n = 8) received LF rTMS + MI + active ES interventions, and those in control group (n = 9) received LF rTMS + MI + sham ES interventions. Interventions were performed 5 days a week for 2 weeks, for a total of 10 sessions. All participants were given the same dosage of conventional rehabilitation during the study period. The primary outcome measure was the UE Fugl-Meyer Assessment (FMA). The secondary outcome measures were the shoulder abduction and finger extension scores, modified Barthel Index, Purdue Pegboard Test, and finger tapping test. All scores were measured before and just after the intervention.
      Results: After the 2-week intervention period, the FMA and modified Barthel Index scores were improved in both groups compared to baseline assessment (P < .001 in the experimental group and P = .008 in the control group). Of note, the change in FMA scores was significantly higher in the experimental group compared with that of the control group (P = .04).
      Conclusion: These results suggest that the use of LF rTMS + MI combined with additional ES lead to greater improvement of UE motor function after stroke. As such, this intervention may be a promising adjuvant therapy in UE motor training.
      Competing Interests: The authors have no funding and conflicts of interest to disclose.
      (Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.)
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    • Publication Date:
      Date Created: 20210903 Date Completed: 20210910 Latest Revision: 20230103
    • Publication Date:
      20240829
    • Accession Number:
      PMC8416012
    • Accession Number:
      10.1097/MD.0000000000027170
    • Accession Number:
      34477175