Congenital Hypothyroidism and the Deleterious Effects on Auditory Function and Language Skills: A Narrative Review.

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  • Additional Information
    • Source:
      Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101555782 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2392 (Print) Linking ISSN: 16642392 NLM ISO Abbreviation: Front Endocrinol (Lausanne) Subsets: MEDLINE
    • Publication Information:
      Original Publication: [Lausanne : Frontiers Research Foundation]
    • Subject Terms:
      Language*; Congenital Hypothyroidism/*complications ; Hearing/*physiology ; Hearing Loss/*etiology ; Language Disorders/*etiology; Child ; Congenital Hypothyroidism/physiopathology ; Hearing Loss/physiopathology ; Humans ; Language Disorders/physiopathology
    • Abstract:
      Congenital hypothyroidism (CH) is an endocrine disease commonly found in newborns and is related to the absence or reduction of thyroid hormones (THs), which are essential for development since intrauterine life. Children with CH can develop hearing problems as THs are crucial for the auditory pathway's development and maturation. Sensory deprivations, especially in hearing disorders at early ages of development, can impair language skills, literacy, and behavioral, cognitive, social, and psychosocial development. In this review we describe clinical and molecular aspects linking CH and hearing loss.
      Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
      (Copyright © 2021 Andrade, Alves and Ramos.)
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    • Contributed Indexing:
      Keywords: auditory system; congenital hypothyroidism; hearing loss; hypothyroidism; thyroid
    • Publication Date:
      Date Created: 20210827 Date Completed: 20211220 Latest Revision: 20231107
    • Publication Date:
      20231107
    • Accession Number:
      PMC8382885
    • Accession Number:
      10.3389/fendo.2021.671784
    • Accession Number:
      34447350