Beyond tics: movement disorders in patients with Tourette syndrome.

Publisher: Springer-Verlag Country of Publication: Austria NLM ID: 9702341 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1435-1463 (Electronic) Linking ISSN: 03009564 NLM ISO Abbreviation: J Neural Transm (Vienna) Subsets: MEDLINE

Original Publication: Wien ; New York : Springer-Verlag, 1996-

Chorea* ; Movement Disorders*/epidemiology ; Movement Disorders*/etiology ; Tic Disorders*/complications ; Tic Disorders*/epidemiology ; Tics*/epidemiology ; Tics*/etiology ; Tourette Syndrome*/complications ; Tourette Syndrome*/epidemiology; Humans

Background: Tics are the hallmark of Tourette syndrome (TS). However, TS patients may have a particular vulnerability to develop other movement disorders (MDs), such as dystonia, chorea, stereotypy, and other hyperkinetic disorders that may be wrongly attributed to tics.
Materials and Methods: We studied a cohort of 201 patients with motor and phonic tics associated with TS to determine if they have additional, co-existent, MDs.
Results: There were 67 (33.3%) patients with comorbid non-tic MDs. Phenomenology-wise, piano-playing movements resembling chorea or myoclonus, were the most common non-tic movement, observed in 11% of cases, followed by stereotypies (8.0%), tremor, dystonia and parkinsonism, 5.0% each. Drug-induced was the most common etiology (6.0%), followed by functional movement disorders (5.0%) and tardive phenomena (5.0%). No clear etiology was identified in most patients. Piano-playing movements, were associated with a younger age at onset (P = 0.004) and younger age at presentation (P < 0.001). Patients with drug-induced movements and tardive phenomena had a lower frequency of craniofacial tics. FMDs, and idiopathic MDS showed no specific associations with TS. Tic severity was not a predictor of any co-existent MD.
Conclusion: About a third of patients with TS present with comorbid MDs which should be differentiated and distinguished from tics as their etiopathogenesis and treatment may be different.
(© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature.)

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Keywords: Chorea minima; Piano-playing movements, tics, functional movement disorders; Psychogenic; Tardive

Date Created: 20210724 Date Completed: 20211027 Latest Revision: 20211116

20240829

10.1007/s00702-021-02386-0

34302221