Community-Based Physical Rehabilitation After Percutaneous Coronary Intervention for Acute Myocardial Infarction.

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  • Author(s): Xiao M;Xiao M; Li Y; Li Y; Guan X; Guan X
  • Source:
    Texas Heart Institute journal [Tex Heart Inst J] 2021 Jun 01; Vol. 48 (2).
  • Publication Type:
    Journal Article; Randomized Controlled Trial
  • Language:
    English
  • Additional Information
    • Source:
      Publisher: published in the Cardiovascular Surgical Research Laboratories, Texas Heart Institute Country of Publication: United States NLM ID: 8214622 Publication Model: Print Cited Medium: Internet ISSN: 1526-6702 (Electronic) Linking ISSN: 07302347 NLM ISO Abbreviation: Tex Heart Inst J Subsets: MEDLINE
    • Publication Information:
      Original Publication: Houston, TX : published in the Cardiovascular Surgical Research Laboratories, Texas Heart Institute, c1982-
    • Subject Terms:
      Myocardial Infarction*/diagnosis ; Myocardial Infarction*/surgery ; Percutaneous Coronary Intervention*/adverse effects; Humans ; Stroke Volume ; Treatment Outcome ; Ventricular Function, Left
    • Abstract:
      To determine whether a community-based physical rehabilitation program could improve the prognosis of patients who had undergone percutaneous coronary intervention after acute myocardial infarction, we randomly divided 164 consecutive patients into 2 groups of 82 patients. Patients in the rehabilitation group underwent 3 months of supervised exercise training, then 9 months of community-based, self-managed exercise; patients in the control group received conventional treatment. The primary endpoint was major adverse cardiac events (MACE) during the follow-up period (25 ± 15.4 mo); secondary endpoints included left ventricular ejection fraction, 6-minute walk distance, and laboratory values at 12-month follow-up. During the study period, the incidence of MACE was significantly lower in the rehabilitation group (13.4% vs 24.4%; P <0.01). Cox proportional hazards regression analysis indicated a significantly lower risk of MACE in the rehabilitation group (hazard ratio=0.56; 95% CI, 0.37-0.82; P=0.01). At 12 months, left ventricular ejection fraction and 6-minute walk distance in the rehabilitation group were significantly greater than those in the control group (both P <0.01), and laboratory values also improved. These findings suggest that community-based physical rehabilitation significantly reduced MACE risk and improved cardiac function and physical stamina in patients who underwent percutaneous coronary intervention after acute myocardial infarction.
      (© 2021 by the Texas Heart® Institute, Houston.)
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    • Contributed Indexing:
      Keywords: Cardiac rehabilitation/methods; combined modality therapy/methods; exercise therapy/methods; health promotion; myocardial infarction/rehabilitation; patient compliance; percutaneous coronary intervention/rehabilitation; prospective studies; quality indicators, health care; treatment outcome
    • Publication Date:
      Date Created: 20210617 Date Completed: 20211028 Latest Revision: 20220531
    • Publication Date:
      20240829
    • Accession Number:
      PMC8262830
    • Accession Number:
      10.14503/THIJ-19-7103
    • Accession Number:
      34139763