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MOGONET integrates multi-omics data using graph convolutional networks allowing patient classification and biomarker identification.
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- Author(s): Wang T;Wang T; Shao W; Shao W; Huang Z; Huang Z; Huang Z; Tang H; Tang H; Zhang J; Zhang J; Ding Z; Ding Z; Huang K; Huang K; Huang K; Huang K
- Source:
Nature communications [Nat Commun] 2021 Jun 08; Vol. 12 (1), pp. 3445. Date of Electronic Publication: 2021 Jun 08.- Publication Type:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't- Language:
English - Source:
- Additional Information
- Source: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
- Publication Information: Original Publication: [London] : Nature Pub. Group
- Subject Terms:
- Abstract: To fully utilize the advances in omics technologies and achieve a more comprehensive understanding of human diseases, novel computational methods are required for integrative analysis of multiple types of omics data. Here, we present a novel multi-omics integrative method named Multi-Omics Graph cOnvolutional NETworks (MOGONET) for biomedical classification. MOGONET jointly explores omics-specific learning and cross-omics correlation learning for effective multi-omics data classification. We demonstrate that MOGONET outperforms other state-of-the-art supervised multi-omics integrative analysis approaches from different biomedical classification applications using mRNA expression data, DNA methylation data, and microRNA expression data. Furthermore, MOGONET can identify important biomarkers from different omics data types related to the investigated biomedical problems.
- References: AMIA Jt Summits Transl Sci Proc. 2018 May 18;2017:197-206. (PMID: 29888072)
Cancer Res. 2007 Dec 15;67(24):11612-20. (PMID: 18089790)
Genes (Basel). 2019 Mar 21;10(3):. (PMID: 30901858)
Mol Cancer. 2006 Jun 19;5:24. (PMID: 16784538)
Oncotarget. 2017 Mar 7;8(10):16122-16143. (PMID: 28179587)
PLoS Comput Biol. 2017 Nov 3;13(11):e1005752. (PMID: 29099853)
Bioinformatics. 2009 Nov 15;25(22):2906-12. (PMID: 19759197)
Clin Cancer Res. 2018 Mar 15;24(6):1248-1259. (PMID: 28982688)
J Oncol Transl Res. 2018;4(1):. (PMID: 29780974)
Brain Imaging Behav. 2017 Apr;11(2):401-409. (PMID: 27743375)
Nat Rev Neurosci. 2012 Jan 05;13(2):77-93. (PMID: 22218207)
Nat Commun. 2021 Jun 8;12(1):3445. (PMID: 34103512)
BMC Bioinformatics. 2012 Dec 08;13:326. (PMID: 23216969)
Noncoding RNA. 2019 Nov 19;5(4):. (PMID: 31752366)
BMC Bioinformatics. 2015 Aug 19;16:261. (PMID: 26283178)
Cancer Res. 2005 Aug 15;65(16):7065-70. (PMID: 16103053)
Neurobiol Aging. 2000 May-Jun;21(3):383-421. (PMID: 10858586)
Bioinformatics. 2013 Oct 15;29(20):2596-602. (PMID: 23990414)
Expert Opin Ther Targets. 2016;20(4):389-91. (PMID: 26853544)
J Periodontol. 2008 Aug;79(8 Suppl):1535-43. (PMID: 18673008)
BMC Bioinformatics. 2011 Jun 22;12:253. (PMID: 21693065)
J Cell Physiol. 2020 Feb;235(2):638-657. (PMID: 31254280)
Clin Cancer Res. 2012 Dec 15;18(24):6702-13. (PMID: 23060431)
Curr Alzheimer Res. 2012 Jul;9(6):628-45. (PMID: 22471860)
Neurobiol Dis. 2019 Jul;127:410-418. (PMID: 30923004)
Pharmacol Ther. 2005 Aug;107(2):198-211. (PMID: 15907343)
J Am Med Inform Assoc. 2015 Jan;22(1):109-20. (PMID: 25002459)
Alzheimers Dement. 2019 Jun;15(6):788-798. (PMID: 30935898)
Stat Med. 2016 Feb 10;35(3):368-81. (PMID: 26365903)
Oncogene. 2019 Sep;38(37):6445-6460. (PMID: 31324889)
Bioinformatics. 2019 Sep 1;35(17):3055-3062. (PMID: 30657866)
PLoS Med. 2010 May 25;7(5):e1000279. (PMID: 20520800)
Nature. 2012 Oct 4;490(7418):61-70. (PMID: 23000897)
Nat Methods. 2014 Mar;11(3):333-7. (PMID: 24464287)
Cancer Epidemiol Biomarkers Prev. 2002 Nov;11(11):1361-8. (PMID: 12433712)
Cell Res. 2009 Apr;19(4):439-48. (PMID: 19238171)
Neuropeptides. 2018 Aug;70:76-86. (PMID: 29807653)
Bioinformatics. 2007 Jan 1;23(1):30-7. (PMID: 17130137)
Front Pharmacol. 2019 Apr 16;10:395. (PMID: 31040784)
J Clin Oncol. 2009 Mar 10;27(8):1160-7. (PMID: 19204204)
IEEE Trans Neural Netw. 1997;8(3):654-62. (PMID: 18255668)
Front Biosci. 2008 Jan 01;13:1318-27. (PMID: 17981632)
Mol Cell. 2006 Nov 3;24(3):367-81. (PMID: 17081988)
Cancer Sci. 2012 Oct;103(10):1820-5. (PMID: 22738294)
Oncotarget. 2016 Mar 15;7(11):13106-21. (PMID: 26894864)
Nucleic Acids Res. 2016 May 5;44(8):e71. (PMID: 26704973)
Nucleic Acids Res. 2016 Oct 14;44(18):8772-8785. (PMID: 27382066)
Front Genet. 2019 Mar 08;10:166. (PMID: 30906311)
Sci Data. 2018 Aug 07;5:180142. (PMID: 30084846)
Brief Bioinform. 2018 Mar 1;19(2):325-340. (PMID: 28011753)
Brief Bioinform. 2019 Jul 19;20(4):1269-1279. (PMID: 29272335)
Mach Learn Med Imaging. 2015;9352:255-262. (PMID: 26900608)
BioData Min. 2013 Dec 20;6(1):23. (PMID: 24359638)
Nature. 2015 Jul 16;523(7560):313-7. (PMID: 26153859)
Nucleic Acids Res. 2009 Jul;37(Web Server issue):W305-11. (PMID: 19465376)
J Alzheimers Dis. 2008 May;14(1):27-41. (PMID: 18525125)
Breast Cancer Res Treat. 2010 May;121(1):41-51. (PMID: 19590950) - Grant Information: R01 EB025018 United States EB NIBIB NIH HHS; U54 AG065181 United States AG NIA NIH HHS
- Accession Number: 0 (Biomarkers)
- Publication Date: Date Created: 20210609 Date Completed: 20210615 Latest Revision: 20240216
- Publication Date: 20240216
- Accession Number: PMC8187432
- Accession Number: 10.1038/s41467-021-23774-w
- Accession Number: 34103512
- Source:
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