Polytetrafluoroethylene coating fragments during neuroendovascular therapy: An analysis of two damaged microguidewires.

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
Read More Add to Saved list
  • Additional Information
    • Source:
      Publisher: Sage Publications Country of Publication: United States NLM ID: 9602695 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2385-2011 (Electronic) Linking ISSN: 15910199 NLM ISO Abbreviation: Interv Neuroradiol Subsets: MEDLINE
    • Publication Information:
      Publication: 2015- : Thousand Oaks, CA : Sage Publications
      Original Publication: Milan, Udine, Italy : Edizioni del Centauro, [1995-
    • Subject Terms:
      Polymers* ; Polytetrafluoroethylene*; Humans
    • Abstract:
      Cerebral polymer coating embolism from intravascular devices represents a potentially serious complication to endovascular therapy (EVT). We report two cases of neuroendovascular treatment where filamentous polymer fragments were noted possibly due to damage of the surface coating during manipulation and backloading of microguidewires. As the exact origin of the debris was initially not known, microguidewires and fragments were examined with light microscopy, stereomicroscopy, scanning electron microscopy and attenuated-total-reflection Fourier transform infrared spectroscopy. Fragments consisted of polytetrafluoroethylene and silicone oil stemming from the proximal shaft of a standard microguidewire. To our knowledge, this is the first report of polytetrafluoroethylene coating fragments created during EVT. Future studies should assess the mechanism of polymer coating delamination and its potential consequences during EVT including inadvertent fragment migration into the cerebral circulation.
    • References:
      J Neurointerv Surg. 2019 Jan;11(1):80-83. (PMID: 30026256)
      Cardiovasc Pathol. 2017 Sep - Oct;30:45-54. (PMID: 28759819)
      Eur Urol. 1998 Sep;34(3):233-6. (PMID: 9732200)
      Circ Cardiovasc Interv. 2015 Feb;8(2):e001816. (PMID: 25582439)
      AJNR Am J Neuroradiol. 1997 Nov-Dec;18(10):1886-9. (PMID: 9403448)
      Am J Surg Pathol. 2008 Sep;32(9):1310-6. (PMID: 18636015)
      AJNR Am J Neuroradiol. 1997 Aug;18(7):1243-51. (PMID: 9282849)
      J Neurosurg. 2014 Feb;120(2):365-74. (PMID: 24320006)
      AJNR Am J Neuroradiol. 2015 Nov;36(11):2121-6. (PMID: 26294650)
      NMC Case Rep J. 2019 Dec 18;7(1):5-10. (PMID: 31938675)
      J Thorac Cardiovasc Surg. 1979 Jun;77(6):875-9. (PMID: 155758)
      Hum Pathol. 2016 Jul;53:178-90. (PMID: 27072640)
      Br J Urol. 1995 May;75(5):666-9. (PMID: 7613805)
      J Neurointerv Surg. 2019 Dec;11(12):1191-1196. (PMID: 31103995)
    • Contributed Indexing:
      Keywords: Attenuated-total-reflection Fourier transform infrared spectroscopy; hydrophilic polymers; microguidewire coating; polymer coating embolism; polytetrafluoroethylene; silicone oil
    • Accession Number:
      0 (Polymers)
      9002-84-0 (Polytetrafluoroethylene)
    • Publication Date:
      Date Created: 20210527 Date Completed: 20220309 Latest Revision: 20230202
    • Publication Date:
      20230202
    • Accession Number:
      PMC8905087
    • Accession Number:
      10.1177/15910199211015127
    • Accession Number:
      34039049