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Systemic Immune Inflammation Index: A Novel Predictor of Contrast-Induced Nephropathy in Patients With Non-ST Segment Elevation Myocardial Infarction.
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- Author(s): Kelesoglu S;Kelesoglu S; Yilmaz Y; Yilmaz Y; Elcık D; Elcık D; Çetınkaya Z; Çetınkaya Z; Inanc MT; Inanc MT; Dogan A; Dogan A; Oguzhan A; Oguzhan A; Kalay N; Kalay N
- Source:
Angiology [Angiology] 2021 Oct; Vol. 72 (9), pp. 889-895. Date of Electronic Publication: 2021 Apr 08.- Publication Type:
Journal Article- Language:
English - Source:
- Additional Information
- Source: Publisher: Sage Publications Country of Publication: United States NLM ID: 0203706 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1940-1574 (Electronic) Linking ISSN: 00033197 NLM ISO Abbreviation: Angiology Subsets: MEDLINE
- Publication Information: Publication: Thousand Oaks, CA : Sage Publications
Original Publication: New York [etc.] Angiology Research Foundation. - Subject Terms: Contrast Media/*administration & dosage ; Inflammation/*diagnosis ; Kidney Diseases/*chemically induced ; Non-ST Elevated Myocardial Infarction/*therapy ; Percutaneous Coronary Intervention/*adverse effects; Adult ; Aged ; Blood Platelets ; Female ; Humans ; Inflammation/blood ; Kidney Diseases/blood ; Kidney Diseases/diagnosis ; Lymphocyte Count ; Lymphocytes ; Male ; Middle Aged ; Neutrophils ; Non-ST Elevated Myocardial Infarction/blood ; Non-ST Elevated Myocardial Infarction/diagnostic imaging ; Patient Admission ; Platelet Count ; Predictive Value of Tests ; Retrospective Studies ; Risk Assessment ; Risk Factors ; Time Factors ; Treatment Outcome
- Abstract: We investigated whether the systemic immune inflammation index (SII) on admission is an independent risk factor that predicts the development of contrast-induced nephropathy (CIN) in patients with non-ST segment elevation myocardial infarction (NSTEMI) who underwent percutaneous coronary intervention (PCI). A total of 429 patients with NSTEMI were enrolled in the study. Contrast-induced nephropathy was defined as an increase in serum creatinine level of ≥0.5 mg/dL or ≥25% above baseline within 72 hour after the procedure. Patients were divided into 2 groups: with and without CIN. Demographics, clinical risk factors, angiographic and laboratory parameters, CIN incidence, and SII score were compared between the 2 groups. Non-ST segment elevation myocardial infarction patients, who developed CIN, had higher glucose levels ( P = .009), neutrophil counts ( P < .001), platelet counts ( P < .001), neutrophil-lymphocyte ratios ( P < .001), high sensitivity C-reactive protein levels ( P = .009), and SII levels ( P < .001) than those who did not develop CIN. The receiver operating characteristic curve analysis showed that at a cutoff of 933.2, the value of SII exhibited 77.6% sensitivity and 69.2% specificity for detecting CIN. Our study showed that the SII levels on admission were independently associated with CIN development after PCI in patients with NSTEMI.
- Comments: Comment in: Angiology. 2021 Oct;72(9):896. (PMID: 34096340)
- Contributed Indexing: Keywords: contrast-induced nephropathy; non-ST segment elevation myocardial infarction; percutaneous coronary intervention; systemic immune inflammation index
- Accession Number: 0 (Contrast Media)
- Publication Date: Date Created: 20210408 Date Completed: 20211004 Latest Revision: 20211012
- Publication Date: 20231215
- Accession Number: 10.1177/00033197211007738
- Accession Number: 33827291
- Source:
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