The Physiological TMPRSS2 Inhibitor HAI-2 Alleviates SARS-CoV-2 Infection.

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  • Additional Information
    • Source:
      Publisher: American Society For Microbiology Country of Publication: United States NLM ID: 0113724 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1098-5514 (Electronic) Linking ISSN: 0022538X NLM ISO Abbreviation: J Virol Subsets: MEDLINE
    • Publication Information:
      Publication: Washington Dc : American Society For Microbiology
      Original Publication: Baltimore, American Society for Microbiology.
    • Subject Terms:
      COVID-19/*metabolism ; Membrane Glycoproteins/*metabolism ; SARS-CoV-2/*metabolism ; Serine Endopeptidases/*metabolism; Animals ; COVID-19/genetics ; Chlorocebus aethiops ; HEK293 Cells ; Humans ; Membrane Glycoproteins/genetics ; SARS-CoV-2/genetics ; Serine Endopeptidases/genetics ; Vero Cells
    • References:
      JAMA. 2020 Apr 7;323(13):1239-1242. (PMID: 32091533)
      J Biol Chem. 2021 Jan-Jun;296:100135. (PMID: 33268377)
      J Virol. 2018 Sep 12;92(19):. (PMID: 30021905)
      Nat Med. 2020 Aug;26(8):1200-1204. (PMID: 32555424)
      Oncogene. 2020 Sep;39(37):5950-5963. (PMID: 32778768)
      Proc Natl Acad Sci U S A. 2020 Mar 31;117(13):7001-7003. (PMID: 32165541)
      Nat Struct Mol Biol. 2011 Feb;18(2):135-41. (PMID: 21217702)
      Antimicrob Agents Chemother. 2016 Oct 21;60(11):6532-6539. (PMID: 27550352)
      J Virol. 2013 Dec;87(23):12552-61. (PMID: 24027332)
      Nat Commun. 2020 Mar 27;11(1):1620. (PMID: 32221306)
      Cell. 2020 Apr 16;181(2):271-280.e8. (PMID: 32142651)
      Pathol Int. 2018 Mar;68(3):145-158. (PMID: 29431273)
    • Contributed Indexing:
      Keywords: HAI-2; SARS-CoV-2; TMPRSS2
    • Accession Number:
      0 (Membrane Glycoproteins)
      0 (SPINT2 protein, human)
      EC 3.4.21.- (Serine Endopeptidases)
      EC 3.4.21.- (TMPRSS2 protein, human)
    • Publication Date:
      Date Created: 20210401 Date Completed: 20210531 Latest Revision: 20211125
    • Publication Date:
      20240829
    • Accession Number:
      PMC8315915
    • Accession Number:
      10.1128/JVI.00434-21
    • Accession Number:
      33789993