Natural Killer Cells at the Tumors Microenvironment.

NK cells have the innate ability to recognize and eliminate transformed cells. However, tumors still form and progress in seemingly immune-competent individuals. The tumor microenvironment controls NK recruitment and maintenance in situ. Current understanding of NK basic biology explain in part their limitations, that might turn the anti-cancerous devotion into a tumor progression outcome. Recent progress in understanding of the evasion from NK recognition and counterattack against the killer cells are discussed, along with unresolved questions. [ABSTRACT FROM AUTHOR]

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