Intussusception caused by intestinal neoplasia in mature rainbow trout (Oncorhynchus mykiss, Walbaum 1792).

Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 9881188 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2761 (Electronic) Linking ISSN: 01407775 NLM ISO Abbreviation: J Fish Dis Subsets: MEDLINE

Original Publication: Oxford, Blackwell Scientific Publications.

Oncorhynchus mykiss*; Adenocarcinoma/*veterinary ; Fish Diseases/*etiology ; Intestinal Neoplasms/*veterinary ; Intussusception/*veterinary; Adenocarcinoma/complications ; Adenocarcinoma/pathology ; Animals ; Fish Diseases/pathology ; Fisheries ; Hungary ; Intestinal Neoplasms/complications ; Intestinal Neoplasms/pathology ; Intussusception/etiology

The aquaculture industry is growing and includes the farming and breeding of more than 580 aquatic species worldwide. The rainbow trout (Oncorhynchus mykiss, Walbaum 1792) is the most commonly bred trout species in Hungary. As broodfish form the basis of most fish farms, investigation into tumours occurring in trout, although under-researched, has proven to be a valuable and necessary field of study. During our investigation, we examined a broodstock of 3- to 6-year-old rainbow trouts (800) affected with idiopathic intestinal tumours (3%) which had consequentially led to ileus (40%). While performing necropsy, initial pathological observations showed intussusceptions. Tumours were discovered upon opening the body cavity, as well as metastasis forming in the livers and in the vessels of the gills. Histopathological and immunohistochemical tests allowed us to identify the neoplasms. The primary adenocarcinoma was found to have been developed within the intestines of the fish. The tumour tissue broke through the basal membrane and infiltrated the propria, protruding asymmetrically into the lumen of the mid-intestines, causing it to narrow significantly. This subsequently led to passage disorders, invagination of the intestinal segment and finally the emaciation of the fish. Histopathological and immunohistochemical inspection of the tumour cells displayed a high mitotic index, confirming malignancy.
(© 2021 The Authors. Journal of Fish Diseases published by John Wiley & Sons Ltd.)

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Keywords: Oncorhynchus mykiss; Rainbow trout; adenocarcinoma; invagination

Date Created: 20210310 Date Completed: 20210707 Latest Revision: 20210707

20240829

10.1111/jfd.13347

33690895