Virus-inducible IGFALS facilitates innate immune responses by mediating IRAK1 and TRAF6 activation.

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  • Additional Information
    • Source:
      Publisher: Chinese Society of Immunology;; _b Nature Pub. Group Country of Publication: China NLM ID: 101242872 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2042-0226 (Electronic) Linking ISSN: 16727681 NLM ISO Abbreviation: Cell Mol Immunol Subsets: MEDLINE
    • Publication Information:
      Original Publication: Beijing, China : Tokyo, Japan : Chinese Society of Immunology; Nature Pub. Group, 2010-
    • Subject Terms:
      Immunity, Innate*; Carrier Proteins/*metabolism ; Glycoproteins/*metabolism ; Influenza A virus/*physiology ; Interleukin-1 Receptor-Associated Kinases/*metabolism ; Sendai virus/*physiology ; TNF Receptor-Associated Factor 6/*metabolism; A549 Cells ; Animals ; Hep G2 Cells ; Humans ; Mice ; Signal Transduction
    • References:
      Brubaker, S. W. et al. Innate immune pattern recognition: a cell biological perspective. Annu Rev. Immunol. 33, 257–290 (2015). (PMID: 10.1146/annurev-immunol-032414-112240)
      Boisclair, Y. R. et al. The acid-labile subunit (ALS) of the 150 kDa IGF-binding protein complex: an important but forgotten component of the circulating IGF system. J. Endocrinol. 170, 63–70 (2001). (PMID: 10.1677/joe.0.1700063)
      Firth, S. M. et al. D440N mutation in the acid-labile subunit of insulin-like growth factor complexes inhibits secretion and complex formation. Mol. Endocrinol. 25, 307–314 (2011). (PMID: 10.1210/me.2010-0295)
      van Duyvenvoorde, H. A. et al. Homozygous and heterozygous expression of a novel mutation of the acid-labile subunit. Eur. J. Endocrinol. 159, 113–120 (2008). (PMID: 10.1530/EJE-08-0081)
      Zheng, C. et al. Inflammatory role of TLR-MyD88 signaling in multiple sclerosis. Front Mol. Neurosci. 12, 314 (2019). (PMID: 10.3389/fnmol.2019.00314)
      Cohen, P. & Strickson, S. The role of hybrid ubiquitin chains in the MyD88 and other innate immune signalling pathways. Cell Death Differ. 24, 1153–1159 (2017). (PMID: 10.1038/cdd.2017.17)
      Dainichi, T. et al. Immune control by TRAF6-mediated pathways of epithelial cells in the EIME (epithelial immune microenvironment). Front Immunol. 10, 1107 (2019). (PMID: 10.3389/fimmu.2019.01107)
    • Grant Information:
      81971494 National Natural Science Foundation of China (National Science Foundation of China)
    • Accession Number:
      0 (Carrier Proteins)
      0 (Glycoproteins)
      0 (TNF Receptor-Associated Factor 6)
      0 (insulin-like growth factor binding protein, acid labile subunit)
      EC 2.7.11.1 (IRAK1 protein, human)
      EC 2.7.11.1 (Interleukin-1 Receptor-Associated Kinases)
    • Publication Date:
      Date Created: 20210305 Date Completed: 20220126 Latest Revision: 20220716
    • Publication Date:
      20231215
    • Accession Number:
      PMC8167138
    • Accession Number:
      10.1038/s41423-021-00649-0
    • Accession Number:
      33664485