Illness perceptions and beliefs about medication: impact on health-related quality of life in adolescent kidney transplant recipients.

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  • Additional Information
    • Source:
      Publisher: Munksgaard Country of Publication: Denmark NLM ID: 9802574 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1399-3046 (Electronic) Linking ISSN: 13973142 NLM ISO Abbreviation: Pediatr Transplant Subsets: MEDLINE
    • Publication Information:
      Original Publication: Copenhagen ; Malden, MA : Munksgaard, c1997-
    • Subject Terms:
      Attitude to Health* ; Culture* ; Quality of Life*; Kidney Transplantation/*psychology; Adolescent ; Female ; Humans ; Male ; Self Report
    • Abstract:
      Adolescents diagnosed with chronic kidney disease (CKD) who undergo kidney transplantation have to adjust to pervasive effects of chronic illness and life-long treatment maintenance, alongside normative developmental stressors. The way in which adolescent transplant recipients experience and think about their illness as well as their medication regimen can be a crucial factor impacting psychosocial outcomes. Participants were 26 adolescent kidney transplant recipients (μ = 16.8 years, σ = 1.69 years) who completed self-report surveys during a clinic visit. Multiple linear regressions were used to investigate whether adolescents' beliefs about medications and attitudes and perceptions of their illness are associated with their overall quality of life. Adolescents' negative illness perceptions contributed to lower transplant-specific health-related quality of life ratings (ΔR 2 =.305, p < .01). Additionally, adolescent beliefs about their specific medication regimens (ie, personal medication concerns) (ΔR 2 =.342, p < .01), and general beliefs about medication use (ie, harm, overuse) (ΔR 2 =.241, p < .05) also contribute significantly to the variance in their overall quality of life ratings. Adolescent transplant patients in older grades and those in special education endorsed lower quality of life. Cognitive components (eg, beliefs, perceptions) of an adolescent kidney transplant recipient's experience contribute to transplant-related quality of life outcomes. This highlights a point of intervention where cognitive change interventions may be utilized and efficacious in improving health outcomes.
      (© 2021 Wiley Periodicals LLC.)
    • References:
      Centers for Disease Control and Prevention (CDC). Chronic Kidney Disease Surveillance System-United States. Accessed July 7, 2020. http://www.cdc.gov/ckd.
      Devine K, Reed-Knight B, Loiselle K, Simons L, Mee L, Blount R. Predictors of long-term health-related quality of life in adolescent solid organ transplant recipients. J Pediatr Psychol. 2011;36(8):891-901.
      Kelly MM. Children and adolescents with chronic kidney disease: a population at risk for more than just kidney disease. Nephrol Nurs J. 2016;43(1):67.
      Maslow GR, Haydon AA, Ford CA, et al. Young adult outcomes of children growing up with chronic illness: an analysis of the national longitudinal study of adolescent health. Arch Pediatr Adol Med. 2011;165(3):256-261.
      Johnson RJ, Gerson AC, Harshman LA, et al. A longitudinal examination of parent-reported emotional-behavioral functioning of children with mild to moderate chronic kidney disease. Pediatr Nephrol. 2020;35(7):1287-1295.
      Francis A, Didsbury MS, van Zwieten A, et al. Quality of life of children and adolescents with chronic kidney disease: a cross-sectional study. Arch Dis Child. 2019;104(2):134-140.
      Marciano RC, Bouissou-Soares CM, Diniz JSS, et al. Behavioral disorders and low quality of life in children and adolescents with chronic kidney disease. Pediatr Nephrol. 2011;26(2):281-290.
      Selewski DT, Massengill SF, Troost JP, et al. Gaining the patient reported outcomes measurement information system (PROMIS) perspective in chronic kidney disease: a Midwest pediatric nephrology consortium study. Pediatr Nephrol. 2014;29(12):2347-2356.
      Kogon AJ, Matheson MB, Flynn JT, et al. Depressive symptoms in children with chronic kidney disease. J Pediatr. 2016;168:164-170.
      Karczewski SA, Keane M, Agarwal BN. Psychological aspects and challenges of living with chronic kidney disease for adolescents. In: Haddad MN, Winnicki E, Nguyen S, eds. Adolescents with Chronic Kidney Disease. Springer International Publishing; 2019:17-42.
      Varni JW, Limbers CA, Burwinkle TM. Impaired health-related quality of life in children and adolescents with chronic conditions: a comparative analysis of 10 disease clusters and 33 disease categories/severities utilizing the PedsQL Generic Core Scales. Health Qual Life Out. 2007;5(1):43.
      Heath J, MacKinlay D, Watson AR, et al. Self-reported quality of life in children and young people with chronic kidney disease. Pediatr Nephrol. 2011;26(5):767-773.
      Sundaram SS, Landgraf JM, Neighbors K, et al. Adolescent health-related quality of life following liver and kidney transplantation. Am J Transplant. 2007;7(4):982-989.
      Kucukarslan SN. A review of published studies of patients’ illness perceptions and medication adherence: Lessons learned and future directions. Res Social Admin Pharm. 2012;8(5):371-382.
      Weinman J, Petrie KJ, Moss-morris R, Horne R. The illness perception questionnaire: a new method for assessing the cognitive representation of illness. Psychol Health. 1996;11(3):431-445.
      Massey EK, Tielen M, Laging M, et al. The role of goal cognitions, illness perceptions and treatment beliefs in self-reported adherence after kidney transplantation: A cohort study. J Psychosom Res. 2013;75(3):229-234.
      Jonker D, Deacon E, Van Rensburg E, Segal D. Illness perception of adolescents with well-controlled type 1 diabetes mellitus. Health Psychol Open. 2018;5(2):205.
      Benyamini Y, Goner-Shilo D, Lazarov A. Illness perception and quality of life in patients with contact dermatitis. Contact Dermatitis. 2012;67(4):193-199.
      Atwa ZTH, Wahed WYA. The impact of illness perception and socio-clinico-demographic factors on perceived quality of life in children and adolescents with thalassemia intermedia. Pediatr Blood Cancer. 2019;66(7):e27735.
      Asnani M, Barton-Gooden A, Grindley M, Knight-Madden J. Utility of paediatric quality of life and revised illness perception questionnaires in adolescents with sickle cell disease. Vulner Child Youth Studies. 2016;11(1):1-12.
      Wilski M, Tasiemski T. Illness perception, treatment beliefs, self-esteem, and self-efficacy as correlates of self-management in multiple sclerosis. Acta Neurol Scand. 2015;133(5):338-345.
      Harvey JN, Lawson VL. The importance of health belief models in determining self-care behaviour in diabetes. Diabetic Med. 2009;26(1):5-13.
      Snethen JA, Broome ME, Bartels J, Warady BA. Adolescents’ perception of living with end stage renal disease. Pediatr Nurs. 2001;27(2):159.
      Sawicki GS, Sellers DE, Robinson WM. Associations between illness perceptions and health-related quality of life in adults with cystic fibrosis. J Psychosom Res. 2011;70(2):161-167.
      Zelikovsky N, Dobson T, Norman J. Medication beliefs and perceived barriers in adolescent renal transplant patients and their parents. Pediatr Nephrol. 2011;26(6):953-959.
      Drangsholt SH, Cappelen UW, Von der Lippe N, et al. Beliefs about medicines in dialysis patients and after renal transplantation. Hemodial Int. 2019;23(1):117-125.
      Wileman V, Farrington K, Wellsted D, et al. Medication beliefs are associated with phosphate binder non-adherence in hyperphosphatemic haemodialysis patients. Br J Health Psychol. 2015;20(3):563-578.
      Bünemann M, Bauer-Hohmann M, Klewitz F, et al. Beliefs about immunosuppressant medication and correlates in a German kidney transplant population. J Psychosom Res. 2020;109.
      Wray J, Waters S, Radley-Smith R, Sensky T. Adherence in adolescents and young adults following heart or heart-lung transplantation. Pediatr Transplant. 2006;10(6):694-700.
      Zanetti-Yabur A, Rizzo A, Hayde N, et al. Exploring the usage of a mobile phone application in transplanted patients to encourage medication compliance and education. Am J Surg. 2017;214(4):743-747.
      Weissberg-Benchell J, Zielinski TE, Rodgers S, et al. Pediatric health-related quality of life: feasibility, reliability and validity of the PedsQL™ transplant module. Am J Transplant. 2010;10(7):1677-1685.
      Moss-Morris R, Weinman J, Petrie KJ, et al. The revised illness perception questionnaire (IPQ-R). Psychol Health. 2002;17:1-6.
      Broadbent E, Petrie KJ, Main J, Weinman J. The brief illness perception questionnaire. J Psychosom Res. 2006;60:631-637.
      Horne R, Weinman J, Hankins M. The beliefs about medications questionnaire: the development of a new method for assessing the cognitive representation of medication. Psychol Health. 1999;14:1-24.
      IBM Corp. IBM SPSS Statistics for Windows, Version 25.0. Armonk, NY: IBM Corp; 2017.
      Mohammad S, Hormaza L, Neighbors K, et al. Health status in young adults two decades after pediatric liver transplantation. Am J Transplant. 2012;12(6):1486-1495.
      Cushman GK, Stolz MG, Blount RL, Reed B. Executive functioning in pediatric solid organ transplant recipients: A meta-analytic review. Transplant. 2020;104(2):357-366.
      Harshman LA, Johnson RJ, Matheson MB, et al. Academic achievement in children with chronic kidney disease: a report from the CKiD cohort. Pediatr Nephrol. 2019;34:689-696.
    • Contributed Indexing:
      Keywords: chronic kidney disease; cognitions; illness perceptions; quality of life; well-being
    • Publication Date:
      Date Created: 20210216 Date Completed: 20220120 Latest Revision: 20220120
    • Publication Date:
      20240628
    • Accession Number:
      10.1111/petr.13988
    • Accession Number:
      33590948