Growth capability of epidemic influenza viruses in Japan since the 2009 H1N1 pandemic.

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
  • Additional Information
    • Source:
      Publisher: Springer-Verlag Country of Publication: Austria NLM ID: 7506870 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-8798 (Electronic) Linking ISSN: 03048608 NLM ISO Abbreviation: Arch Virol Subsets: MEDLINE
    • Publication Information:
      Original Publication: Wien, New York, Springer-Verlag.
    • Subject Terms:
    • Abstract:
      The correlation of viral growth capability (n = 156) with the viral load in nasopharyngeal swabs (n = 76) was assessed. Epidemic influenza A/H1N1, A/H3N2, and B viruses showed a wide range of growth capability (10 4 -10 11 copies/mL) in Madin-Darby canine kidney cells. The growth was correlated with the nasopharyngeal viral load (r = 0.53). Six selected strains showed growth-dependent cell death (r = 0.96) in a growth kinetics assay. Epidemic influenza viruses exhibit a wide range of growth capability. Growth capability should be considered one of the key factors in disease prognosis.
    • References:
      Chidlow G, Harnett G, Williams S, Levy A, Speers D, Smith DW (2010) Duplex real-time reverse transcriptase PCR assays for rapid detection and identification of pandemic (H1N1) 2009 and seasonal influenza A/H1, A/H3, and B viruses. J Clin Microbiol 48:862–866. (PMID: 10.1128/JCM.01435-09)
      Clark TW, Ewings S, Medina MJ, Batham S, Curran MD, Parmar S, Nicholson KG (2016) Viral load is strongly associated with length of stay in adults hospitalised with viral acute respiratory illness. J Infect 73:598–606. (PMID: 10.1016/j.jinf.2016.09.001)
      Duchamp MB, Casalegno JS, Gillet Y, Frobert E, Bernard E, Escuret V, Billaud G, Valette M, Javouhey E, Lina B, Floret D, Morfin F (2010) Pandemic A(H1N1)2009 influenza virus detection by real time RT-PCR: is viral quantification useful? Clin Microbiol Infect 16:317–321. (PMID: 10.1111/j.1469-0691.2010.03169.x)
      Granados A, Peci A, McGeer A, Gubbay JB (2017) Influenza and rhinovirus viral load and disease severity in upper respiratory tract infections. J Clin Virol 86:14–19. (PMID: 10.1016/j.jcv.2016.11.008)
      Hara M, Morihara M, Takao S, Fukuda S, Shimazu Y, Tanizawa Y, Matsuo T (2012) Influenza viral load and rapid influenza diagnostic tests in children and adults. Diagn Microbiol Infect Dis 73:99–100. (PMID: 10.1016/j.diagmicrobio.2012.01.018)
      Herold S, Becker C, Ridge KM, Budinger GR (2015) Influenza virus-induced lung injury: pathogenesis and implications for treatment. Eur Respir J 45:1463–1478. (PMID: 10.1183/09031936.00186214)
      König R, Stertz S, Zhou Y, Inoue A, Hoffmann HH, Bhattacharyya S, Alamares JG, Tscherne DM, Ortigoza MB, Liang Y, Gao Q, Andrews SE, Bandyopadhyay S, De Jesus P, Tu BP, Pache L, Shih C, Orth A, Bonamy G, Miraglia L, Ideker T, García-Sastre A, Young JA, Palese P, Shaw ML, Chanda SK (2010) Human host factors required for influenza virus replication. Nature 463:813–817. (PMID: 10.1038/nature08699)
      Lalueza A, Folgueira D, Muñoz-Gallego I, Trujillo H, Laureiro J, Hernández-Jiménez P, Moral-Jiménez N, Castillo C, Ayuso B, Díaz-Pedroche C, Torres M, Arrieta E, Arévalo-Cañas C, Madrid O, Lumbreras C (2019) Influence of viral load in the outcome of hospitalized patients with influenza virus infection. Eur J Clin Microbiol Infect Dis 38:667–673. (PMID: 10.1007/s10096-019-03514-1)
      Lambert SB, Whiley DM, O’Neill NT, Andrews EC, Canavan FM, Bletchly C, Siebert DJ, Sloots TP, Nissen MD (2008) Comparing nose-throat swabs and nasopharyngeal aspirates collected from children with symptoms for respiratory virus identification using real-time polymerase chain reaction. Pediatrics 122:e615-620. (PMID: 10.1542/peds.2008-0691)
      Lee N, Chan PK, Hui DS, Rainer TH, Wong E, Choi KW, Lui GC, Wong BC, Wong RY, Lam WY, Chu IM, Lai RW, Cockram CS, Sung JJ (2009) Viral loads and duration of viral shedding in adult patients hospitalized with influenza. J Infect Dis 200:492–500. (PMID: 10.1086/600383)
      Lee YS, Seong BL (1998) Nucleotides in the panhandle structure of the influenza B virus virion RNA are involved in the specificity between influenza A and B viruses. J Gen Virol 79(Pt 4):673–681. (PMID: 10.1099/0022-1317-79-4-673)
      Li CC, Wang L, Eng HL, You HL, Chang LS, Tang KS, Lin YJ, Kuo HC, Lee IK, Liu JW, Huang EY, Yang KD (2010) Correlation of pandemic (H1N1) 2009 viral load with disease severity and prolonged viral shedding in children. Emerg Infect Dis 16:1265–1272. (PMID: 10.3201/eid1608.091918)
      Mahony JB, Chong S, Luinstra K, Petrich A, Smieja M (2010) Development of a novel bead-based multiplex PCR assay for combined subtyping and oseltamivir resistance genotyping (H275Y) of seasonal and pandemic H1N1 influenza A viruses. J Clin Virol 49:277–282. (PMID: 10.1016/j.jcv.2010.08.006)
      Ngaosuwankul N, Noisumdaeng P, Komolsiri P, Pooruk P, Chokephaibulkit K, Chotpitayasunondh T, Sangsajja C, Chuchottaworn C, Farrar J, Puthavathana P (2010) Influenza A viral loads in respiratory samples collected from patients infected with pandemic H1N1, seasonal H1N1 and H3N2 viruses. Virol J 7:75. (PMID: 10.1186/1743-422X-7-75)
      Pechirra P, Nunes B, Coelho A, Ribeiro C, Goncalves P, Pedro S, Castro LC, Rebelo-de-Andrade H (2005) Molecular characterization of the HA gene of influenza type B viruses. J Med Virol 77:541–549. (PMID: 10.1002/jmv.20490)
      Sheth AN, Patel P, Peters PJ (2011) Influenza and HIV: lessons from the 2009 H1N1 influenza pandemic. Curr HIV/AIDS Rep 8:181–191. (PMID: 10.1007/s11904-011-0086-4)
      Spencer S, Thompson MG, Flannery B, Fry A (2019) Comparison of respiratory specimen collection methods for detection of influenza virus infection by reverse transcription-PCR: a literature review. J Clin Microbiol 57:e00027–19.
      Taubenberger JK, Morens DM (2008) The pathology of influenza virus infections. Annu Rev Pathol 3:499–522. (PMID: 10.1146/annurev.pathmechdis.3.121806.154316)
      To KK, Chan KH, Li IW, Tsang TY, Tse H, Chan JF, Hung IF, Lai ST, Leung CW, Kwan YW, Lau YL, Ng TK, Cheng VC, Peiris JS, Yuen KY (2010) Viral load in patients infected with pandemic H1N1 2009 influenza A virus. J Med Virol 82:1–7. (PMID: 10.1002/jmv.21664)
      Tsou TP, Shao PL, Lu CY, Chang LY, Kao CL, Lee PI, Yang PC, Lee CY, Huang LM (2012) Viral load and clinical features in children infected with seasonal influenza B in 2006/2007. J Formos Med Assoc 111:83–87. (PMID: 10.1016/j.jfma.2010.10.001)
      Tsuneki A, Itagaki A, Tsuchie H, Tokuhara M, Okada T, Narai S, Kasagi M, Tanaka K, Kageyama S (2013) Reduced replication capacity of influenza A(H1N1)pdm09 virus during the 2010–2011 winter season in Tottori, Japan. J Med Virol 85:1871–1877. (PMID: 10.1002/jmv.23700)
      Wong JY, Kelly H, Cheung CM, Shiu EY, Wu P, Ni MY, Ip DK, Cowling BJ (2015) Hospitalization fatality risk of influenza A(H1N1)pdm09: a systematic review and meta-analysis. Am J Epidemiol 182:294–301. (PMID: 10.1093/aje/kwv054)
      Zhou B, Donnelly ME, Scholes DT, St George K, Hatta M, Kawaoka Y, Wentworth DE (2009) Single-reaction genomic amplification accelerates sequencing and vaccine production for classical and Swine origin human influenza a viruses. J Virol 83:10309–10313. (PMID: 10.1128/JVI.01109-09)
    • Grant Information:
      15K19228; 18K17353 Japan Society for the Promotion of Science
    • Accession Number:
      0 (RNA, Viral)
    • Publication Date:
      Date Created: 20210213 Date Completed: 20210319 Latest Revision: 20210319
    • Publication Date:
      20231215
    • Accession Number:
      PMC7880649
    • Accession Number:
      10.1007/s00705-021-04976-5
    • Accession Number:
      33580378