[Comparative study of the detection of serum folate with improved microbial assay and electrochemiluminescence method].

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  • Additional Information
    • Source:
      Publisher: Wei sheng yan jiu bian ji bu Country of Publication: China NLM ID: 9426367 Publication Model: Print Cited Medium: Print ISSN: 1000-8020 (Print) Linking ISSN: 10008020 NLM ISO Abbreviation: Wei Sheng Yan Jiu Subsets: MEDLINE
    • Publication Information:
      Publication: Beijing Shi : Wei sheng yan jiu bian ji bu
      Original Publication: Beijing Shi : "Wei sheng yan jiu" bian ji bu,
    • Subject Terms:
      Folic Acid Deficiency*; Biological Assay ; Folic Acid ; Humans ; Nutritional Status
    • Abstract:
      Objective: To compare the result of serum folate determined by improved microbial assay and electrochemiluminescence method, and to look for the relationship between them, so as to provide basis for the assessment of nutrition status of folate in population.
      Methods: A total of 258 serum samples were examined by improved microbial assay and electrochemiluminescence method. The correlation and consistence of the two method were analyzed.
      Results: The result showed that the correlation coefficient of the two method was 0. 885, which indicated that the result of two method were highly correlated. Results of Bland-Altman method showed that 94. 5% of the values were within the consistency limit, and the Kappa value of Kappa test was 0. 665. The result of consistency analysis showed that there were some differences between the two methods, and the result of serum folate tested by improved microbial assay were higher than that of electrochemiluminescence method in general.
      Conclusion: The result of serum folate tested by electrochemiluminescence were highly correlated with the improved microbial assay, yet there are some differences in the consistency result between the two methods. Evaluating the nutrition status of folate by electrochemiluminescence may lead to a higher number of folate deficiency.
    • Contributed Indexing:
      Keywords: electrochemiluminescence; folate; improved microbial assay
    • Accession Number:
      935E97BOY8 (Folic Acid)
    • Publication Date:
      Date Created: 20210201 Date Completed: 20210202 Latest Revision: 20210202
    • Publication Date:
      20231215
    • Accession Number:
      10.19813/j.cnki.weishengyanjiu.2021.01.019
    • Accession Number:
      33517971