[Diagnostic accuracy of a hysteroscopic score for the detection of endometrial cancer in patients with postmenopausal bleeding and endometrial thickening].

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  • Additional Information
    • Source:
      Publisher: Sociedad Colombiana De Obstetricia Y Ginecologia Country of Publication: Colombia NLM ID: 0404263 Publication Model: Print Cited Medium: Internet ISSN: 2463-0225 (Electronic) Linking ISSN: 00347434 NLM ISO Abbreviation: Rev Colomb Obstet Ginecol Subsets: MEDLINE
    • Publication Information:
      Publication: Bogota : Sociedad Colombiana De Obstetricia Y Ginecologia
      Original Publication: Bogotá [1950?]-
    • Subject Terms:
      Postmenopause*; Endometrial Neoplasms/*diagnosis ; Hysteroscopy/*methods ; Uterine Hemorrhage/*pathology; Aged ; Biopsy ; Cross-Sectional Studies ; Endometrial Neoplasms/epidemiology ; Endometrial Neoplasms/pathology ; Female ; Humans ; Middle Aged ; Sensitivity and Specificity
    • Abstract:
      Objective: To assess the diagnostic accuracy of hysteroscopic scores in endometrial cancer.
      Methods: Diagnostic accuracy study assembled within a cross-sectional study that included patients with postmenopausal bleeding and endometrial thickening greater than 5 mm in whom hysteroscopy was performed and then compared with endometrial biopsy as the diagnostic gold standard, in two high complexity hospitals. Clinical, sociodemographic variables, as well as hysteroscopic scores and the results of endometrial tissue histopathology were measured. Sensitivity and specificity, likelihood ratios and area under the curve with their respective confidence intervals were estimated in the analysis.
      Results: With a 9 % prevalence of endometrial cancer, the hysteroscopic assessment system was shown to have 75 % sensitivity (95 % CI; 30.1- 95.43), 95,1 % specificity (95 % CI; 83.9-98.7), a positive likelihood ratio of 15.38 (95 %; CI 3.55- 66.56), a negative likelihood ratio of 0.26 and area under the curve of 85 %.
      Conclusions: The standardized hysteroscopic assessment system was found to have an acceptable sensitivity for screening in patients with postmenopausal bleeding and endometrial thickening (≥ 5 mm). Further studies with larger sample sizes are required in order to arrive at a more precise estimation of the operational characteristics of the hysteroscopic assessment system for the detection of endometrial cancer.
      Competing Interests: None declared
      (Copyright© 2020 This is an open-access article distributed under the terms of the Creative Commons Attribution License by-nc-nd/4.0.)
    • Contributed Indexing:
      Keywords: histeroscopia; Uterine hemorrhage; endometrial neoplasms; hemorragia uterina; hysteroscopy; neoplasias endometriales; posmenopausia; postmenopause
      Local Abstract: [Publisher, Spanish; Castilian] EXACTITUD DIAGNÓSTICA DE UNA ESCALA HISTEROSCÓPICA PARA LA DETECCIÓN DE CÁNCER ENDOMETRIAL EN PACIENTES CON SANGRADO POSMENOPÁUSICO Y ENGROSAMIENTO ENDOMETRIAL. [Publisher, Spanish; Castilian] Evaluar la exactitud diagnóstica del sistema de puntaje histeroscópico de cáncer endometrial. [Publisher, Spanish; Castilian] Estudio de exactitud diagnóstica ensamblado en estudio transversal, que incluyó pacientes con sangrado posmenopáusico y engrosamiento endometrial mayor o igual a 5 mm, a quienes se practicó histeroscopia, cuyo resultado se comparó con la biopsia endometrial como patrón de oro diagnóstico, en dos hospitales de alta complejidad. Se midieron variables sociodemográficas, clínicas, puntaje de evaluación histeroscópica y resultado histopatológico de tejido endometrial. En el análisis se estimó sensibilidad, especificidad, razones de probabilidades y área bajo la curva con sus respectivos intervalos de confianza. [Publisher, Spanish; Castilian] Con una prevalencia del cáncer endometrial del 9 %, el sistema de evaluación por histeroscopia mostró una sensibilidad de 75 % (IC 95 %: 30,1-95,43), especificidad de 95,1 % (IC 95 %: 83,9- 98,7), una razón de probabilidades positiva de 15,38 (IC 95 %: 3,55-66,56), una razón de probabilidades negativa de 0,26 y un área bajo la curva del 85 %. [Publisher, Spanish; Castilian] el sistema de evaluación endometrial histeroscópico estandarizado mostró una sensibilidad aceptable para hacer la tamización en pacientes con sangrado posmenopáusico y engrosamiento endometrial (≥ 5 mm). Se requiere la realización de estudios con un mayor tamaño muestral que permitan hacer una estimación más precisa de las características operativas de este sistema de evaluación histeroscópico para la detección de cáncer endometrial.
    • Publication Date:
      Date Created: 20201128 Date Completed: 20210927 Latest Revision: 20210927
    • Publication Date:
      20221213
    • Accession Number:
      10.18597/rcog.3445
    • Accession Number:
      33247887