Investigation of human bocavirus in pediatric patients with respiratory tract infection.

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  • Additional Information
    • Source:
      Publisher: Open Learning on Enteric Pathogens Country of Publication: Italy NLM ID: 101305410 Publication Model: Electronic Cited Medium: Internet ISSN: 1972-2680 (Electronic) Linking ISSN: 19722680 NLM ISO Abbreviation: J Infect Dev Ctries Subsets: MEDLINE
    • Publication Information:
      Original Publication: [Italy?] : Open Learning on Enteric Pathogens
    • Subject Terms:
      Coinfection/*virology ; Human bocavirus/*isolation & purification ; Parvoviridae Infections/*virology ; Respiratory Tract Infections/*virology ; Virus Diseases/*epidemiology; Adolescent ; Child ; Child, Preschool ; Coinfection/epidemiology ; Cross-Sectional Studies ; Female ; Human bocavirus/genetics ; Human bocavirus/pathogenicity ; Humans ; Incidence ; Infant ; Infant, Newborn ; Male ; Parvoviridae Infections/epidemiology ; Respiratory Tract Infections/epidemiology ; Retrospective Studies ; Turkey/epidemiology
    • Abstract:
      Introduction: Human bocavirus (HBoV) is a linear single-stranded DNA virus belonging to the Parvoviridae family. This study aimed to investigate the incidence of HBoV and co-infections in pediatric patients with symptoms of viral respiratory tract infection.
      Methodology: This study included 2,310 patients between the ages of 0-18 in whom HBoV and other respiratory tract viral pathogens were analyzed in nasopharyngeal swab specimens.
      Results: In the pediatric age group, HBoV was found in 4.5% (105/2310) of the patients and higher in children between the ages of 1 and 5. Mixed infection was detected in 43.8% (46/105) of HBoV positive patients (p = 0.10). Mono and mixed infection rates were higher in outpatients than in inpatients (p < 0.05). Respiratory syncytial virus was significantly higher than the other respiratory viral pathogens (p < 0.001).
      Conclusions: This study is important as it is one of the rare studies performed on the incidence of HBoV in the Marmara region. In pediatric age group, the incidence of HBoV was found 4.5%. The incidence rate of HBoV in this study was similar to those in studies around the world, but close to low rates. The incidence of HBoV was found higher especially among children between the ages of 1-5 in this study. In addition to the incidence of HBoV, accompanying co-infections in the pediatric age group were also investigated in this study. Since concurrence of RSV, HRV and hMPV with HBoV was the most common it must be considered that there may be more than one agents in patients with symptoms of respiratory tract infection.
      Competing Interests: No Conflict of Interest is declared
      (Copyright (c) 2020 Ayfer Bakir, Nuran Karabulut, Sema Alacam, Sevim Mese, Ayper Somer, Ali Agacfidan.)
    • Contributed Indexing:
      Keywords: Human bocavirus; Respiratory syncytial virus; respiratory tract infections
    • Publication Date:
      Date Created: 20201111 Date Completed: 20210902 Latest Revision: 20210902
    • Publication Date:
      20240829
    • Accession Number:
      10.3855/jidc.12553
    • Accession Number:
      33175716