Tissue Engineering for Periodontal Ligament Regeneration: Biomechanical Specifications.

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  • Additional Information
    • Source:
      Publisher: American Society Of Mechanical Engineers Country of Publication: United States NLM ID: 7909584 Publication Model: Print Cited Medium: Internet ISSN: 1528-8951 (Electronic) Linking ISSN: 01480731 NLM ISO Abbreviation: J Biomech Eng
    • Publication Information:
      Publication: New York Ny : American Society Of Mechanical Engineers
      Original Publication: [New York] American Society of Mechanical Engineers.
    • Subject Terms:
      Periodontal Ligament*/cytology ; Periodontal Ligament*/physiology ; Tissue Engineering*/methods ; Regeneration*; Humans ; Biomechanical Phenomena ; Animals ; Mechanical Phenomena
    • Abstract:
      The periodontal biomechanical environment is very difficult to investigate. By the complex geometry and composition of the periodontal ligament (PDL), its mechanical behavior is very dependent on the type of loading (compressive versus tensile loading; static versus cyclic loading; uniaxial versus multiaxial) and the location around the root (cervical, middle, or apical). These different aspects of the PDL make it difficult to develop a functional biomaterial to treat periodontal attachment due to periodontal diseases. This review aims to describe the structural and biomechanical properties of the PDL. Particular importance is placed in the close interrelationship that exists between structure and biomechanics: the PDL structural organization is specific to its biomechanical environment, and its biomechanical properties are specific to its structural arrangement. This balance between structure and biomechanics can be explained by a mechanosensitive periodontal cellular activity. These specifications have to be considered in the further tissue engineering strategies for the development of an efficient biomaterial for periodontal tissues regeneration.
      (Copyright © 2021 by ASME.)
    • Publication Date:
      Date Created: 20201017 Date Completed: 20240724 Latest Revision: 20240724
    • Publication Date:
      20240726
    • Accession Number:
      10.1115/1.4048810
    • Accession Number:
      33067629