Prospects for the ex situ liver machine perfusion in Brazil.

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  • Author(s): Boteon YL;Boteon YL;Boteon YL; Boteon APCDS; Boteon APCDS
  • Source:
    Revista do Colegio Brasileiro de Cirurgioes [Rev Col Bras Cir] 2020 Oct 07; Vol. 47, pp. e20202610. Date of Electronic Publication: 2020 Oct 07 (Print Publication: 2020).
  • Publication Type:
    Journal Article
  • Language:
    English; Portuguese
  • Additional Information
    • Source:
      Publisher: Colégio Brasileiro de Cirurgiões Country of Publication: Brazil NLM ID: 7809515 Publication Model: eCollection Cited Medium: Internet ISSN: 1809-4546 (Electronic) Linking ISSN: 01006991 NLM ISO Abbreviation: Rev Col Bras Cir Subsets: MEDLINE
    • Publication Information:
      Original Publication: Rio de Janeiro : Colégio Brasileiro de Cirurgiões, [1974?]-
    • Subject Terms:
      Liver Transplantation* ; Liver, Artificial* ; Organ Preservation* ; Perfusion* ; Tissue Donors*; Brazil ; Humans ; Liver
    • Abstract:
      Brazil, like most countries in the world, experiences the expansion of extended criteria donors, mainly due to the aging of the population and the obesity epidemic. Concerns regarding the quality of these organs along with the vast territorial areas of the country compromise the utilization rate of livers from donors and aggravate the discrepancy between the number of liver transplants performed and the needed. Ex situ liver machine perfusion offers superior preservation for livers from extended criteria donors, limiting cold ischaemia time and offering the possibility of evaluation of their function before transplantation as well as the reconditioning of marginal organs. Objections such as the financial cost, difficulty in transporting the device between hospitals, and demand of trained professionals in the handling of the device must be pondered with the possibility of increasing the number of transplants and the utilisation rate of donor organs. The optimal use of this resource, through the careful selection of donors and the appropriate technical and scientific knowledge, can ensure an effective and successful implementation of this technology.
    • Publication Date:
      Date Created: 20201014 Date Completed: 20201021 Latest Revision: 20201021
    • Publication Date:
      20240829
    • Accession Number:
      10.1590/0100-6991e-20202610
    • Accession Number:
      33053064